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Scholar Results 1 - 10 of about 193 citing Vaessen: A Polymorphism in the gene for IGF-I. (0.11 sec) 

Circulating concentrations of insulin-like growth factor-I and development of glucose …


MS Sandhu, AH Heald, JM Gibson, JK … - The Lancet, 2002 - Elsevier
At 4·5 years of follow-up, 51 (8%) of 615 participants developed impaired
glucose tolerance or type-2 diabetes. After adjustment for correlates of IGF-I
and risk factors for glucose intolerance, the odds ratio for risk of ...
Cited by 211 - Related articles - All 6 versions

Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, …

- oxfordjournals.org
MS Sandhu, DB Dunger, EL Giovannucci - JNCI Journal of the National Cancer Institute, 2002 - jnci.oxfordjournals.org
Secular changes and worldwide variations in incidence rates of colorectal
cancer, along with results from twin and migrant studies, provide compelling
evidence that environmental factors influence the risk of this disease. ...
Cited by 168 - Related articles - BL Direct - All 7 versions

A survey of genetic and epigenetic variation affecting human gene expression


T Pastinen, R Sladek, S Gurd, A Sammak, B … - Physiological genomics, 2004 - Am Physiological Soc
The identification of human sequence polymorphisms that regulate gene expression
is key to understanding human genetic diseases. We report a survey of human
genes that demonstrate allelic differences in gene expression, reflecting ...
Cited by 158 - Related articles - BL Direct - All 5 versions

Association between genetic variation in the gene for insulin-like growth factor-l and low …


N Vaessen, JA Janssen, P Heutink, A Hofman … - The Lancet, 2002 - Elsevier
Low birthweight is associated with later risk of type 2 diabetes and related
disorders. We aimed to show that a polymorphism in the gene for insulin-like
growth factor-l, which has proved to raise risk of type 2 diabetes and ...
Cited by 132 - Related articles - BL Direct - All 6 versions

The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary …

- endojournals.org
HF Escobar-Morreale, M Luque-Ramirez, JL … - Endocrine Reviews, 2005 - Endocrine Soc
The elucidation of the molecular genetic basis of these disorders has been
burdened by the heterogeneity in the diagnostic criteria used to define PCOS,
the limited sample size of the studies conducted to date, and the lack of ...
Cited by 128 - Related articles - All 6 versions

The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding …

- endojournals.org
GA Laughlin, E Barrett-Connor, MH Criqui, D … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
The IGF system has been implicated in cardiovascular disease (CVD) development.
The prospective association of serum IGF-I and IGF-binding protein-1 (IGFBP-1)
with all cause, ischemic heart disease (IHD), and non-IHD CVD mortality was ...
Cited by 123 - Related articles - BL Direct - All 6 versions

Serum levels of insulin-like growth factor I and its binding proteins in health and disease

- ugeskriftet.dk [PDF] 
A Juul - Growth Hormone & IGF Research, 2003 - Elsevier
Historically, it was suggested that the growth promoting effects of GH were
mediated by a liver derived factor initially termed “sulphation factor” [1]
which was stimulated by GH. At the same time another group of researchers ...
Cited by 121 - Related articles - BL Direct - All 10 versions

Free insulin-like growth factors–measurements and relationships to growth hormone …


J Frystyk - Growth hormone & IGF research, 2004 - Elsevier
IGF-I is a multipotent growth factor with important actions on normal tissue
growth and regeneration. In addition, IGF-I has been suggested to have
beneficial effects on glucose homeostasis due to its glucose lowering and ...
Cited by 107 - Related articles - All 5 versions

Genetics of type 2 diabetes


I Barroso - Diabetic medicine, 2005 - interscience.wiley.com
Type 2 diabetes (T2D) has become a health-care problem worldwide, with the rise
in disease prevalence being all the more worrying as it not only affects the
developed world but also developing nations with fewer resources to cope ...
Cited by 101 - Related articles - All 6 versions

Prospective study of social and other risk factors for incidence of type 2 diabetes in the …


M Kumari, J Head, M Marmot - Archives of Internal Medicine, 2004 - Am Med Assoc
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Cited by 81 - Related articles - BL Direct - All 7 versions


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