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Scholar Results 1 - 10 of about 89 citing Parker: A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is.... (0.11 sec) 

[BOOK] Medical botany: plants affecting human health


MPF Elvin-Lewis - 2003 - books.google.com
SECOND EDiTiON MEDICAL BOTANY PLANTS AFFECTING HUMAN HEALTH WALTER H.
LEWIS MEMORY PF ELVIN-LEWIS ... MEDICAL BOTANY This One 3LNA-WP9-XCSR ... MEDICAL
BOTANY Plants Affecting Human Hcalth Second Edition WALTER H. LEWIS Professor ...
Cited by 299 - Related articles - Library Search - All 10 versions

Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms …


Y Mori, S Otabe, C Dina, K Yasuda, C Populaire, C … - Diabetes, 2002 - Am Diabetes Assoc
The genetic background that predisposes the Japanese population to type 2 diabetes is largely
unknown. Therefore, we conducted a 10-cM genome-wide scan for type 2 diabetes traits in the
359 affected individuals from 159 families, yielding 224 affected sib-pairs of Japanese ...
Cited by 166 - Related articles - BL Direct - All 4 versions

Genomewide linkage analysis of stature in multiple populations reveals several …

- nih.gov
JN Hirschhorn, CM Lindgren, MJ Daly, A Kirby, SF … - The American Journal of …, 2001 - Elsevier
Genomewide linkage analysis has been extremely successful at identification of the genetic
variation underlying single-gene disorders. However, linkage analysis has been less successful
for common human diseases and other complex traits in which multiple genetic and ...
Cited by 144 - Related articles - BL Direct - All 9 versions

A genome-wide scan for loci linked to plasma levels of glucose and HbA1c in a …


JB Meigs, CIM Panhuysen, RH Myers, PWF Wilson, LA … - Diabetes, 2002 - Am Diabetes Assoc
Elevated blood glucose levels are the hallmark of type 2 diabetes as well as a powerful risk factor
for development of the disease. We conducted a genome-wide search for diabetes-related
genes, using measures of glycemia as quantitative traits in 330 pedigrees from the ...
Cited by 130 - Related articles - BL Direct - All 5 versions

A genome scan for type 2 diabetes susceptibility loci in a genetically isolated …

- diabetesjournals.org
MA Permutt, JC Wasson, BK Suarez, J Lin, J Thomas, J … - Diabetes, 2001 - Am Diabetes Assoc
A total of 896 individuals of Ashkenazi Jewish descent were ascertained in Israel from 267 multiplex
families, including 472 sib-pairs affected with type 2 diabetes. A genome-wide scan with average
marker spacing of 9.5 cM revealed five regions on four chromosomes (4q, 8q, 14q, and ...
Cited by 123 - Related articles - BL Direct - All 4 versions

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish …

- nih.gov
CM Lindgren, MM Mahtani, E Widen, MI McCarthy, … - The American Journal of …, 2002 - Elsevier
Type 2 diabetes mellitus is a heterogeneous inherited disorder characterized by chronic hyperglycemia
resulting from pancreatic β-cell dysfunction and insulin resistance. Although the pathogenic mechanisms
are not fully understood, manifestation of the disease most likely requires interaction ...
Cited by 117 - Related articles - BL Direct - All 9 versions

Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34–q35. …

- nih.gov
I Reynisdottir, G Thorleifsson, R Benediktsson, G … - The American Journal of …, 2003 - Elsevier
We report a genomewide linkage study of type 2 diabetes (T2D [MIM 125853]) in the Icelandic
population. A list of type 2 diabetics was cross-matched with a computerized genealogical database
clustering 763 type 2 diabetics into 227 families. The diabetic patients and their relatives ...
Cited by 97 - Related articles - BL Direct - All 14 versions

Growing evidence for diabetes susceptibility genes from genome scan data


MI McCarthy - Current diabetes reports, 2003 - Springer
Introduction Type 2 diabetes (T2D), together with related traits such as obesity and the other
components of the metabolic syn- drome, has emerged as a dominant cause of morbidity and
mortality in societies across the globe [1]. Success in man- aging this “epidemic” of ...
Cited by 87 - Related articles - BL Direct - All 3 versions

Impaired insulin secretion and glucose tolerance in β cell-selective Cav1. 2 Ca2+ …


V Schulla, E Renström, R Feil, S Feil, I Franklin … - The EMBO …, 2003 - pubmedcentral.nih.gov
Insulin is secreted from pancreatic β cells in response to an elevation of cytoplasmic Ca 2+ resulting
from enhanced Ca 2+ influx through voltage-gated Ca 2+ channels. Mouse β cells express several
types of Ca 2+ channel (L-, R- and possibly P/Q-type). β cell-selective ablation of the ...
Cited by 75 - Related articles - All 3 versions

Detecting epistatic interactions contributing to quantitative traits


R Culverhouse, T Klein, W Shannon - Genetic epidemiology, 2004 - interscience.wiley.com
The restricted partition method (RPM) is a partitioning algorithm for examining multi-locus genotypes
as (potentially non-additive) predictors of a quantitative trait. The motivating application was to
develop a robust method to examine quantitative phenotypes for epistasis (gene-gene ...
Cited by 72 - Related articles - BL Direct - All 4 versions


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