D Dietze, M Koenen, K Röhrig, H Horikoshi, H Hauner, … - Diabetes, 2002 - Am Diabetes Assoc Adipocyte factors play a major role in the induction of insulin resistance in skeletal muscle. To
analyze this cross-talk, we established a system of co-culture of human fat and skeletal muscle
cells. Cells of three muscle donors were kept in co-culture with cells of various fat cell ... Cited by 73 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org WG Aschenbach, MF Hirshman, N Fujii, K Sakamoto, … - Diabetes, 2002 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is proposed to stimulate fat and carbohydrate catabolism
to maintain cellular energy status. Recent studies demonstrate that pharmacologic activation
of AMPK and mutations in the enzyme are associated with elevated muscle glycogen ... Cited by 52 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org R Halse, LGD Fryer, JG McCormack, D Carling, SJ … - Diabetes, 2003 - Am Diabetes Assoc We report here use of human myoblasts in culture to study the relationships between cellular
glycogen concentrations and the activities of glycogen synthase (GS) and AMP-activated protein
kinase (AMPK). Incubation of cells for 2 h in the absence of glucose led to a 25% ... Cited by 50 - Related articles - BL Direct - All 5 versions
JN Nielsen, EA Richter - Acta Physiologica Scandinavica, 2003 - edulife.com.br Abstract Glycogen synthase (GS) catalyses the incorporation of uridine diphosphate- glucose
into glycogen in skeletal muscle. In concert with the glucose trans- port step, GS activity is thought
to be rate-limiting in the disposal of glucose as muscle glycogen. Glycogen synthase is ... Cited by 28 - Related articles - View as HTML - BL Direct - All 5 versions
EL Abbot, JG McCormack, C Reynet, DG Hassall, KW … - FEBS J, 2005 - interscience.wiley.com The pyruvate dehydrogenase complex occupies a central and strategic position in muscle intermediary
metabolism and is primarily regulated by phosphorylation/dephosphorylation. The identification
of multiple isoforms of pyruvate dehydrogenase kinase (PDK1–4) and pyruvate ... Cited by 27 - Related articles - All 4 versions
- ►physiology.org J Jensen, E Jebens, EO Brennesvik, J … - American Journal of …, 2006 - Am Physiological Soc Insulin-stimulated glucose uptake and incorporation of glucose into skeletal muscle glycogen
contribute to physiological regulation of blood glucose concentration. In the present study, glucose
handling and insulin signaling in isolated rat muscles with low glycogen (LG, 24-h fasting) ... Cited by 27 - Related articles - BL Direct - All 4 versions
L Pickersgill, GJ Litherland, AS Greenberg, M … - Journal of Biological …, 2007 - ASBMB Elevated non-esterified fatty acids, triglyceride, diacylglycerol, and ceramide have all been associated
with insulin resistance in muscle. We set out to investigate the role of intramyocellular lipid metabolites
in the induction of insulin resistance in human primary myoblast cultures. Muscle cells ... Cited by 23 - Related articles - All 11 versions
S Yeaman, J Armstrong, S Bonavaud, D … - Biochemical Society …, 2001 - bst.portlandpress.com Glucose uptake into muscle and its subsequent storage as glycogen is a crucial factor in energy
homeostasis in skeletal muscle. This process is stimulated acutely by insulin and is impaired
in both insulin-resistant states and in type 2 diabetes mellitus. A signalling pathway ... Cited by 18 - Related articles - Cached - BL Direct - All 9 versions
- ►physiology.org DS Battram, J Shearer, D Robinson, TE … - Journal of Applied …, 2004 - Am Physiological Soc The purpose of this study was to examine the effects of caffeine (Caf) ingestion on pro- (PG) and
macroglycogen (MG) resynthesis in 10 healthy men. Subjects completed two trials, consisting
of a glycogen-depleting exercise, while ingesting either Caf or placebo capsules. ... Cited by 15 - Related articles - BL Direct - All 8 versions
LJ Logie, AE Brown, SJ Yeaman, M Walker - Molecular Genetics and …, 2005 - Elsevier Variation in the calpain 10 gene has been reported to increase susceptibility to type 2
diabetes. Part of this susceptibility appears to be mediated by a decrease in whole body insulin
sensitivity. As skeletal muscle is the primary tissue site of the peripheral insulin resistance ... Cited by 15 - Related articles - All 3 versions
