MJ Redondo, GS Eisenbarth - Diabetologia, 2002 - Springer Type I (insulin-dependent) diabetes mellitus is a het- erogeneous disease with
major subdivisions termed Type 1A (immune-mediated) and Type 1B. Immune-
mediated diabetes is also heterogeneous with ªmono- genicº, oligogenic, ... Cited by 93 - Related articles - BL Direct - All 5 versions
- ►hematologylibrary.org L Frasca, G Fedele, S Deaglio, C Capuano, R … - Blood, 2006 - bloodjournal.hematologylibrary.org CD38, an ectoenzyme and a signaling receptor, is a novel marker of human mature
monocyte-derived dendritic cells (MDDCs). The working hypothesis is that CD38 is
not only a marker but also contributes to functions specifically gained by ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] A Antonelli, P Fallahi, C Nesti, C Pupilli, P … - Clin Exp Immunol, 2001 - pubmedcentral.nih.gov SUMMARY Autoantibodies directed against human CD38 (an enzyme catalysing the
interconversion of NAD1 and cyclic ADP-ribose) have been demonstrated recently
in patients with type 2 diabetes. We tested 220 consecutive Caucasian ... Cited by 28 - Related articles - View as HTML - BL Direct - All 6 versions
- ►physiology.org F Malavasi, S Deaglio, A Funaro, E Ferrero, AL … - Physiological reviews, 2008 - Am Physiological Soc The membrane proteins CD38 and CD157 belong to an evolutionarily conserved
family of enzymes that play crucial roles in human physiology. Expressed in
distinct patterns in most tissues, CD38 (and CD157) cleaves NAD + and NADP ... Cited by 25 - Related articles - All 3 versions
A Falorni, A Brozzetti - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier Islet autoimmunity is made evident by the appearance of islet-cell antibodies
directed against insulin (IAA), glutamic acid decarboxylase (GADA), protein
tyrosine phosphatase IA-2 (IA-2Ab) and other autoantigens. IAA and IA-2Ab ... Cited by 23 - Related articles - All 3 versions
S Takasawa, H Okamoto - International journal of experimental diabetes research, 2002 - pubmedcentral.nih.gov In the early 1980s, we proposed a unifying model for β-cell damage (The OKAMOTO
model), in which poly(ADP-ribose) synthetase/ polymerase (PARP) activation plays
an essential role in the consumption of NAD + , which leads to energy ... Cited by 15 - Related articles - All 6 versions
R Mallone, E Ortolan, S Pinach, M Volante, M … - Diabetologia, 2002 - Springer Aims/hypothesis. Serum anti-CD38 autoantibodies (aAbs) have been reported in 17
to 19% of patients with long-standing Type I (insulin-dependent) diabe- tes
mellitus and Type II (non-insulin-dependent) dia- betes mellitus. Whether ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org JD Johnson, EL Ford, E Bernal-Mizrachi, KL … - Diabetes, 2006 - Am Diabetes Assoc CD38 is a multifunctional enzyme capable of generating metabolites that release
Ca 2+ from intracellular stores, including nicotinic acid adenine dinucleotide
phosphate (NAADP). A number of studies have led to the controversial ... Cited by 8 - Related articles - BL Direct - All 5 versions
R Mallone, PC Perin - DIABETES METABOLISM RESEARCH AND REVIEWS, 2006 - hal.inserm.fr 1 INSERM U580, Institut Necker, Paris, France; ... Short title: Anti-CD38
antibodies in type ? diabetes ... Corresponding Author: Roberto Mallone, MD
INSERM U580 – Bâtiment Sèvres Institut Necker 161 rue de Sèvres 75015 ... Cited by 5 - Related articles - View as HTML - BL Direct - All 6 versions
KM Khoo, CF Chang, J Schubert, E Wondrak … - Protein expression and purification, 2005 - Elsevier CD38 is a type II transmembrane glycoprotein found in myriad mammalian tissues
and cell types. It is known for its involvement in the metabolism of cyclic
ADP-ribose and nicotinic acid adenine dinucleotide phosphate, two ... Cited by 3 - Related articles - All 4 versions
