M Stumvoll, O Tschritter, A Fritsche, H Staiger, W Renn, … - Diabetes, 2002 - Am Diabetes Assoc The adipocyte-derived hormone adiponectin seems to protect from insulin resistance, a key factor in
the pathogenesis of type 2 diabetes. Genome-wide scans have mapped a susceptibility locus for type 2
diabetes and the metabolic syndrome ... Cited by 271 - Related articles - BL Direct - All 5 versions
- ►nih.gov RK Semple, VKK Chatterjee, SO' … - Journal of Clinical …, 2006 - Am Soc Clin Investig The nuclear receptor family of PPARs was named for the ability of the original member to induce
hepatic peroxisome proliferation in mice in response to xenobiotic stimuli. However, studies on the
action and structure of the 3 human ... Cited by 243 - Related articles - BL Direct - All 10 versions
M Stumvoll, H Häring - Diabetes, 2002 - Am Diabetes Assoc Peroxisome proliferator-activated receptor (PPAR)-γ is a transcription factor with a key role in
adipocyte differentiation. The Ala allele of the common Pro12Ala polymorphism in the isoform
PPAR-γ2 is associated with reduced ... Cited by 187 - Related articles - BL Direct - All 5 versions
- ►mcw.edu [PDF] X Yang, M Downes, RT Yu, AL Bookout, W He, M … - Cell, 2006 - Elsevier As sensors for fat-soluble hormones and dietary lipids, oscillations in nuclear receptor (NR)
expression in key metabolic tissues may contribute to circadian entrainment of nutrient and energy
metabolism. Surveying the diurnal ... Cited by 132 - Related articles - All 14 versions
KL Houseknecht, BM Cole, PJ Steele - Domestic Animal Endocrinology, 2002 - Elsevier Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a class of nuclear hormone
receptors intimately involved in the regulation of expression of myriad genes that regulate energy
metabolism, cell differentiation, ... Cited by 103 - Related articles - BL Direct - All 7 versions
- ►eje.org [PDF] JL Gonzalez Sanchez, M Serrano Rios, C … - European Journal of …, 2002 - eje.org Objective: To investigate the role of the Pro12Ala peroxisome proliferator-activated receptor (PPAR)
g-2 polymorphism in the susceptibility to the insulin resistance syndrome and its metabolic compli-
cations in a population-based ... Cited by 68 - Related articles - BL Direct - All 9 versions
A Meirhaeghe, P Amouyel - Molecular Genetics and Metabolism, 2004 - Elsevier Peroxisome proliferator-activated receptor γ (PPARγ) is a transcription factor with a key role in
adipocyte differentiation. Since 1997, studies of rare mutations and common polymorphisms of the
PPARγ gene have enabled us to ... Cited by 65 - Related articles - All 3 versions
CM Damcott, P Sack, AR Shuldiner - … and metabolism clinics of North America, 2003 - Elsevier Obesity has become an epidemic in the United States and worldwide. The 1999–2000 National Health
and Nutrition Examination Survey (NHANES) estimated that 64% of the adult population of the United
States is either overweight or ... Cited by 48 - Related articles - BL Direct - All 3 versions
A Doney, B Fischer, D Frew, A Cumming, D Flavell… - BMC genetics, 2002 - biomedcentral.com We have genotyped a large population with type 2 diabetes (n = 1107), two populations of
non-diabetics from Glasgow (n = 186) and Dundee (n = 254) and also a healthy group undergoing
physical training (n = 148) and ... Cited by 46 - Related articles - Cached - All 13 versions
- ►oxfordjournals.org S Korhonen, S Heinonen, M Hiltunen, S Helisalmi, M … - Human Reproduction, 2003 - ESHRE BACKGROUND: In view of the strong evidence implicating peroxisome proliferator-activated receptor-
(PPAR ) in adiposity and insulin resistance a study was carried out to investigate PPAR genotype
frequencies in women with ... Cited by 45 - Related articles - BL Direct - All 5 versions
