- ►diabetesjournals.org DJ Drucker - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic
peptide (GIP) exert important effects on β-cells to stimulate glucose-dependent
insulin secretion. Both peptides also regulate β-cell proliferation and ... Cited by 283 - Related articles - All 13 versions
- ►physiology.org JJ Holst, J Gromada - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The available evidence suggests that about two-thirds of the insulin response to
an oral glucose load is due to the potentiating effect of gut-derived incretin
hormones. The strongest candidates for the incretin effect are ... Cited by 180 - Related articles - BL Direct - All 4 versions
F Rubino, J Marescaux - Annals of surgery, 2004 - pubmedcentral.nih.gov To the Editor: The conclusion of this study is drawn from a population-based
analysis of 396 patients. The inclusion was based upon the code for operation
radical pan- creaticoduodenectomy or Whipple pro- cedure, which also ... Cited by 171 - Related articles - BL Direct - All 7 versions
- ►rh.dk [PDF] LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ... Cited by 172 - Related articles - All 25 versions
T Vilsbøll, JJ Holst - Diabetologia, 2004 - Springer When glucose is taken orally, insulin secretion is stim- ulated much more than
it is when glucose is infused intravenously so as to result in similar glucose
con- centrations. This effect, which is called the incretin ef- fect and is ... Cited by 144 - Related articles - BL Direct - All 7 versions
- ►aspetjournals.org KE Mayo, LJ Miller, D Bataille, S Dalle, B … - Pharmacological reviews, 2003 - ASPET Peptide hormones within the secretin-glucagon family are expressed in endocrine
cells of the pancreas and gastrointestinal epithelium and in specialized neurons
in the brain, and subserve multiple biological functions, including ... Cited by 141 - Related articles - BL Direct - All 7 versions
JA Pospisilik, SG Stafford, HU Demuth, R … - Diabetes, 2002 - Am Diabetes Assoc The incretins, glucose-dependent insulinotropic polypeptide (GIP) and
glucagon-like peptide 1 (GLP-1) are responsible for >50% of nutrient-stimulated
insulin secretion. After being released into the circulation, GIP and GLP-1 ... Cited by 135 - Related articles - BL Direct - All 6 versions
JG Kim, LL Baggio, DP Bridon, JP Castaigne, … - Diabetes, 2003 - Am Diabetes Assoc The rapid degradation of native glucagon-like peptide 1 (GLP-1) by dipeptidyl
peptidase-IV (DPP-IV) has fostered new approaches for generation of
degradation-resistant GLP-1 analogues. We examined the biological activity ... Cited by 126 - Related articles - BL Direct - All 5 versions
JJ Meier, MA Nauck, WE Schmidt, B Gallwitz - Regulatory peptides, 2002 - Elsevier After the ingestion of fat- and glucose-rich meals, gut hormones are secreted
into the circulation in order to stimulate insulin secretion. This so-called
“incretin effect” is primarily conferred by Glucagon-like peptide 1 ... Cited by 124 - Related articles - All 5 versions
DJ Drucker - eid, 2003 - informahealthcare.com Incretins are peptide hormones, exemplified by glucose-dependent insulino-
tropic peptide and glucagon-like peptide 1 that are released from the gut in
response to nutrient ingestion and enhance glucose-stimulated insulin ... Cited by 118 - Related articles - All 6 versions
