M Merkel, RH Eckel, IJ Goldberg… - The Journal of Lipid Research, 2002 - ASBMB Page 1. 1 Lipoprotein lipase: genetics, lipid uptake and regulation Martin
Merkel 1 , Robert H. Eckel 2 , Ira J. Goldberg 3 1 Department ... Cited by 209 - Related articles - BL Direct - All 4 versions
- ►jbc.org JA Chavez, TA Knotts, LP Wang, G Li, RT … - Journal of Biological Chemistry, 2003 - ASBMB Multiple studies suggest that lipid oversupply to skeletal muscle contributes to
the development of insulin resistance, perhaps by promoting the accumulation of
lipid metabolites capable of inhibiting signal transduction. Herein we ... Cited by 156 - Related articles - BL Direct - All 5 versions
- ►nih.gov HC Chen, SJ Smith, Z Ladha, DR Jensen, LD … - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1) is one of two known
DGAT enzymes that catalyze the final step in mammalian triglyceride synthesis.
DGAT1-deficient mice are resistant to diet-induced obesity through a ... Cited by 128 - Related articles - BL Direct - All 8 versions
K Preiss-Landl, R Zimmermann, G Hämmerle, … - Current opinion in lipidology, 2002 - journals.lww.com Purpose of review The aim of this review is to summarize and discuss recent
advances in the understanding of the physiological role of lipoprotein lipase in
lipid and energy metabolism. Recent findings Studies on the transcriptional ... Cited by 117 - Related articles - BL Direct - All 7 versions
SA Summers - Progress in Lipid Research, 2006 - Elsevier Obesity predisposes individuals to the development of insulin resistance in
skeletal muscle and the liver, and researchers have recently proposed two
mechanisms by which excess adiposity antagonizes insulin action in ... Cited by 114 - Related articles - All 3 versions
CJ Chou, M Haluzik, C Gregory, KR Dietz, C … - Journal of Biological Chemistry, 2002 - ASBMB WY14,643 is a specific peroxisome proliferator-activated receptor α (PPARα)
agonist with strong hypolipidemic effects. Here we have examined the effect of
WY14,643 in the A-ZIP/F-1 mouse, a model of severe lipoatrophic diabetes. ... Cited by 103 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org PJ Voshol, MC Jong, VEH Dahlmans, D Kratky … - Diabetes, 2001 - Am Diabetes Assoc In patients with type 2 diabetes, a strong correlation between accumulation of
intramuscular triclycerides (TGs) and insulin resistance has been found. The aim
of the present study was to determine whether there is a causal relation ... Cited by 66 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org MT Hamilton, DG Hamilton, TW Zderic - Diabetes, 2007 - Am Diabetes Assoc It is not uncommon for people to spend one-half of their waking day sitting,
with relatively idle muscles. The other half of the day includes the often large
volume of nonexercise physical activity. Given the increasing pace of ... Cited by 63 - Related articles - BL Direct - All 7 versions
Y Kamei, J Mizukami, S Miura, M Suzuki, N … - FEBS letters, 2003 - Elsevier Lipoprotein lipase (LPL) plays a role in lipid usage in skeletal muscle by
hydrolyzing plasma triglycerides into fatty acids, which are further utilized
for β-oxidation. Lipid usage is stimulated during fasting, diabetes ... Cited by 55 - Related articles - All 6 versions
- ►jbc.org JA Chavez, WL Holland, J Bar, K Sandhoff, … - Journal of Biological Chemistry, 2005 - ASBMB Recent studies indicate that insulin resistance and type 2 diabetes result from
the accumulation of lipids in tissues not suited for fat storage, such as
skeletal muscle and the liver. To elucidate the mechanisms linking ... Cited by 55 - Related articles - All 6 versions
