- ►nih.gov EM Wintour, KM Moritz, K Johnson, S Ricardo … - The Journal of Physiology, 2003 - Physiological Soc There is some evidence, mainly from rodent studies, that any factor which alters
the final total number of nephrons formed, during nephrogenesis, will result in
hypertension in adult life. Sheep, programmed to become hypertensive by ... Cited by 105 - Related articles - BL Direct - All 6 versions
KM Moritz, M Dodic, EM Wintour - Bioessays, 2003 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 70 - Related articles - BL Direct - All 3 versions
EM Wintour, K Johnson, I Koukoulas, K Moritz … - Placenta, 2003 - Elsevier The concept that 'life before birth' or the 'first environment' is important in
determining subsequent risk for the development of cardiovascular/metabolic
disease is now gaining acceptance. There are substantial data from animal ... Cited by 44 - Related articles - BL Direct - All 9 versions
- ►endojournals.org LS Fetita, E Sobngwi, P Serradas, F Calvo, JF … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Evidence synthesis: Human studies performed in children and adolescents suggest
that offspring who had been exposed to maternal diabetes during fetal life
exhibit higher prevalence of impaired glucose tolerance and markers of ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►pedneph.info [PDF] K Amann, C Plank, J Dötsch - Pediatric Nephrology, 2004 - Springer Abstract There is increasing evidence that primary hy- pertension, coronary
heart disease, and other aspects of the so-called metabolic syndrome that
develop in adult- hood are primed in fetal life or early postnatally. The ... Cited by 25 - Related articles - All 4 versions
M Lampl, P Jeanty - American Journal of Human Biology, 2004 - interscience.wiley.com The prevalence of diabetes is rising worldwide, including women who grew poorly
in early life, presenting intergenerational health problems for their offspring.
It is well documented that fetuses exposed to maternal diabetes during ... Cited by 21 - Related articles - BL Direct - All 2 versions
- ►eur.nl [PDF] M Schreuder, H Delemarre-van de Waal, A … - Kidney Blood Press Res, 2006 - content.karger.com Low birth weight due to intrauterine growth restriction is associated with
various diseases in adulthood, such as hypertension, cardiovascular disease,
insulin resistance and end-stage renal disease. The purpose of this review ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org ML Gross, K Amann, E Ritz - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol It has been proposed that "nephron underdosing," ie, a low number of nephrons at
the time of birth, is linked to essential hypertension and a greater propensity
to develop progressive loss of renal function after renal injury. This ... Cited by 11 - Related articles - All 5 versions
JPD Van Huyen, M Viltard, T Nehiri, N Freund, … - Laboratory investigation, 2007 - nature.com Remodeling of extracellular matrix (ECM) is an important physiological feature
of normal growth and development. Recent studies have emphasized the role of
matrix metalloproteinases (MMP-2 and MMP-9) in normal mouse nephrogenesis. ... Cited by 7 - Related articles - BL Direct - All 7 versions
YW Chen, F Liu, S Tran, Y Zhu, MJ Hebert, JR … - Kidney international, 2006 - nature.com Diabetic mellitus confers a major risk of congenital malformations, and is
associated with diabetic embryopathy, affecting multiple organs including the
kidney. The DNA paired box-2 (Pax-2) gene is essential in nephrogenesis. We ... Cited by 6 - Related articles - BL Direct - All 3 versions
