- ►nih.gov S Yakar, CJ Rosen, WG Beamer, CL Ackert- … - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig IGF-1 is a growth-promoting polypeptide that is essential for normal growth and
development. In serum, the majority of the IGFs exist in a 150-kDa complex
including the IGF molecule, IGF binding protein 3 (IGFBP-3), and the acid ... Cited by 299 - Related articles - BL Direct - All 8 versions
- ►usc.edu [PDF] VD Longo, CE Finch - Science, 2003 - sciencemag.org Note to users. If you're seeing this message, it means that your browser cannot
find this page's style/presentation instructions -- or possibly that you are
using a browser that does not support current Web standards. Find out more ... Cited by 283 - Related articles - All 13 versions
MS Sandhu, AH Heald, JM Gibson, JK … - The Lancet, 2002 - Elsevier At 4·5 years of follow-up, 51 (8%) of 615 participants developed impaired
glucose tolerance or type-2 diabetes. After adjustment for correlates of IGF-I
and risk factors for glucose intolerance, the odds ratio for risk of ... Cited by 211 - Related articles - All 6 versions
- ►oxfordjournals.org MS Sandhu, DB Dunger, EL Giovannucci - JNCI Journal of the National Cancer Institute, 2002 - jnci.oxfordjournals.org Secular changes and worldwide variations in incidence rates of colorectal
cancer, along with results from twin and migrant studies, provide compelling
evidence that environmental factors influence the risk of this disease. ... Cited by 168 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org P Delafontaine, YH Song, Y Li - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc The vascular insulin-like growth factor (IGF)-1 system includes the IGFs, the
IGF-1 receptor (IGF-1R), and multiple binding proteins. This growth factor
system exerts multiple physiologic effects on the vasculature through both ... Cited by 140 - Related articles - BL Direct - All 9 versions
- ►ugeskriftet.dk [PDF] A Juul - Growth Hormone & IGF Research, 2003 - Elsevier Historically, it was suggested that the growth promoting effects of GH were
mediated by a liver derived factor initially termed “sulphation factor” [1]
which was stimulated by GH. At the same time another group of researchers ... Cited by 121 - Related articles - BL Direct - All 10 versions
J Frystyk - Growth hormone & IGF research, 2004 - Elsevier IGF-I is a multipotent growth factor with important actions on normal tissue
growth and regeneration. In addition, IGF-I has been suggested to have
beneficial effects on glucose homeostasis due to its glucose lowering and ... Cited by 107 - Related articles - All 5 versions
- ►aacrjournals.org Y Wu, K Cui, K Miyoshi, L Hennighausen, JE … - Cancer Research, 2003 - AACR Insulin-like growth factors (IGFs) play a crucial role in regulating cell
proliferation and differentiation. The aim of this study was to examine the
potential relationship between serum IGF-I levels and breast cancer risk. ... Cited by 107 - Related articles - BL Direct - All 8 versions
- ►nih.gov S Yakar, J Setser, H Zhao, B Stannard, M … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Liver IGF-1–deficient (LID) mice have a 75% reduction in circulating IGF-1
levels and, as a result, a fourfold increase in growth hormone (GH) secretion.
To block GH action, LID mice were crossed with GH antagonist (GHa) ... Cited by 95 - Related articles - BL Direct - All 6 versions
M Bakay, P Zhao, J Chen, EP Hoffman - Neuromuscular disorders, 2002 - Elsevier We present an assessment of the complete transcriptome of human skeletal muscle
in Duchenne muscular dystrophy patient muscle and non-dystrophic controls (36
RNAs analyzed from ten Duchenne dystrophy and eight controls; 65,000 gene/ ... Cited by 92 - Related articles - All 5 versions
