- ►endojournals.org EE Kershaw, JS Flier - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Adipose tissue is a complex, essential, and highly active metabolic and
endocrine organ. Besides adipocytes, adipose tissue contains connective tissue
matrix, nerve tissue, stromovascular cells, and immune cells. Together ... Cited by 1082 - Related articles - BL Direct - All 8 versions
N Maeda, I Shimomura, K Kishida, H … - Nature medicine, 2002 - nature.com Here we investigated the biological functions of adiponectin/ACRP30, a
fat-derived hormone, by disrupting the gene that encodes it in mice.
Adiponectin/ACRP30-knockout (KO) mice showed delayed clearance of free ... Cited by 1091 - Related articles - BL Direct - All 6 versions
N Maeda, M Takahashi, T Funahashi, S Kihara … - Diabetes, 2001 - Am Diabetes Assoc Insulin resistance and its dreaded consequence, type 2 diabetes, are major
causes of atherosclerosis. Adiponectin is an adipose-specific plasma protein
that possesses anti-atherogenic properties, such as the suppression of ... Cited by 1009 - Related articles - BL Direct - All 4 versions
- ►leptinresearch.org [PDF] RS Ahima, JS Flier - Trends in Endocrinology & Metabolism, 2000 - Elsevier Energy stores are depleted intermittently during sleep–wake cycles and over
prolonged periods during famine or illness. To maintain vital cellular
functions, humans and other mammals consume more calories than is required ... Cited by 738 - Related articles - BL Direct - All 14 versions
- ►ahajournals.org M Kumada, S Kihara, S Sumitsuji, T Kawamoto … - Arteriosclerosis, thrombosis, and vascular biology, 2003 - Am Heart Assoc Methods and Results— The consecutive 225 male patients were enrolled from
inpatients who underwent coronary angiography. Voluntary blood donors (n=225)
matched for age served as controls. Plasma adiponectin levels in the CAD ... Cited by 670 - Related articles - BL Direct - All 5 versions
- ►nih.gov TP Combs, AH Berg, S Obici, PE Scherer, L … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig Intraperitoneal injection of purified recombinant Acrp30 lowers glucose levels
in mice. To gain insight into the mechanism(s) of this hypoglycemic effect,
purified recombinant Acrp30 was infused in conscious mice during a ... Cited by 596 - Related articles - BL Direct - All 8 versions
- ►nih.gov A Xu, Y Wang, H Keshaw, LY Xu, KSL Lam, … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Adiponectin has recently been shown to be a promising candidate for the
treatment of obesity-associated metabolic syndromes. Replenishment of
recombinant adiponectin in mice can decrease hyperglycemia, reverse insulin ... Cited by 595 - Related articles - BL Direct - All 14 versions
AH Berg, TP Combs, PE Scherer… - Trends in Endocrinology and Metabolism, 2002 - cell.com Adipose tissue has long been regarded as a mostly resting tissue that is
dedicated solely to energy storage and release. However, in recent years, this
view has changed dramatically following new insights into the metabolic and ... Cited by 575 - Related articles - Cached - BL Direct - All 6 versions
- ►endojournals.org MW Rajala, PE Scherer - Endocrinology, 2003 - Endocrine Soc Adipose tissue evolved to efficiently store energy for times of caloric
restriction. The large caloric excess common in many Western diets has negated
the need for this thrifty function, leaving adipose tissue ill-equipped to ... Cited by 566 - Related articles - BL Direct - All 7 versions
M Cnop, PJ Havel, KM Utzschneider, DB Carr, … - Diabetologia, 2003 - Springer Aims/hypothesis. Increased intra-abdominal fat is as- sociated with insulin
resistance and an atherogenic li- poprotein profile. Circulating concentrations
of adip- onectin, an adipocyte-derived protein, are decreased with insulin ... Cited by 525 - Related articles - BL Direct - All 5 versions
