- ►ahajournals.org SE Hardt, J Sadoshima - Circulation research, 2002 - Am Heart Assoc Glycogen synthase kinase-3ß (GSK-3ß) is a ubiquitously expressed
constitutively active serine/threonine kinase that phosphorylates cellular
substrates and thereby regulates a wide variety of cellular functions, ... Cited by 204 - Related articles - BL Direct - All 7 versions
L Song, P De Sarno, RS Jope - Journal of Biological Chemistry, 2002 - ASBMB Stress of the endoplasmic reticulum (ER), which is associated with many
neurodegenerative conditions, can lead to the elimination of affected cells by
apoptosis through only partially understood mechanisms. Thapsigargin, which ... Cited by 136 - Related articles - BL Direct - All 5 versions
- ►nih.gov E Beurel, RS Jope - Progress in neurobiology, 2006 - Elsevier Few things can be considered to be more important to a cell than its threshold
for apoptotic cell death, which can be modulated up or down, but rarely in both
directions, by a single enzyme. Therefore, it came as quite a surprise to ... Cited by 76 - Related articles - All 4 versions
RD Loberg, E Vesely, FC Brosius - Journal of Biological Chemistry, 2002 - ASBMB Hypoxia triggers apoptosis in a number of different cell types largely through a
mitochondrial cell death pathway, which can be abrogated for the most part by
enhanced glucose metabolism. The purpose of the current study was to ... Cited by 74 - Related articles - BL Direct - All 3 versions
HS Kim, C Skurk, SR Thomas, A Bialik, T … - Journal of Biological Chemistry, 2002 - ASBMB Glycogen synthase kinase-3β (GSK3β) plays important roles in metabolism,
embryonic development, and tumorigenesis. Here we investigated the role of
GSK3β signaling in vascular biology by examining its function in ... Cited by 77 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org H Kita, J Carmichael, J Swartz, S Muro, A … - Human Molecular Genetics, 2002 - Oxford Univ Press The majority of triplet-repeat diseases are caused by mutated genes with an
extended polyglutamine tract, exemplified by Huntington's disease (HD). In order
to model HD pathogenesis in a controlled system, we developed stable PC12 ... Cited by 41 - Related articles - BL Direct - All 6 versions
- ►cardiovascres.org N Fulop, RB Marchase, JC Chatham - Cardiovascular research, 2007 - cardiovascres.org There is growing recognition that the O-linked attachment of
N-acetyl-glucosamine (O-GlcNAc) on serine and threonine residues of nuclear and
cytoplasmic proteins is a highly dynamic post-translational modification ... Cited by 36 - Related articles - All 7 versions
L Wang, HK Lin, YC Hu, S Xie, L Yang, C … - Journal of Biological Chemistry, 2004 - ASBMB Androgens play important roles in the growth of normal prostate and prostate
cancer via binding to the androgen receptor (AR). In addition to androgens, AR
activity can also be modulated by selective growth factors and/or kinases. ... Cited by 35 - Related articles - BL Direct - All 9 versions
T Suhara, J Magrané, K Rosen, R … - Neurobiology of aging, 2003 - Elsevier The application of β-amyloid (Aβ) is cytotoxic to endothelial cells, promotes
vasoconstriction and impairs nitric oxide (NO) generation or action. However,
there is no information on the effect of intracellular Aβ on endothelial ... Cited by 32 - Related articles - All 9 versions
- ►ahajournals.org KM Hannan, RJ Dilley, ST de Dios, PJ Little - Arteriosclerosis, thrombosis, and vascular biology, 2003 - Am Heart Assoc Methods and Results— Repair of rat aorta after balloon catheter injury in
troglitazone-treated (400 mg/kg per day by mouth) rats showed early acceleration
of reendothelialization and late reduction in neointima formation. ... Cited by 25 - Related articles - BL Direct - All 6 versions
