- ►diabetesjournals.org N Musi, MF Hirshman, J Nygren, M Svanfeldt, … - Diabetes, 2002 - Am Diabetes Assoc Metformin is an effective hypoglycemic drug that lowers blood glucose
concentrations by decreasing hepatic glucose production and increasing glucose
disposal in skeletal muscle; however, the molecular site of metformin ... Cited by 236 - Related articles - BL Direct - All 4 versions
- ►physiology.org WW Winder - Journal of Applied Physiology, 2001 - Am Physiological Soc AMP-activated protein kinase (AMPK) is emerging as an important
energy-sensing/signaling system in skeletal muscle. This kinase is activated
allosterically by 5'-AMP and inhibited allosterically by creatine ... Cited by 215 - Related articles - BL Direct - All 5 versions
B Kemp, D Stapleton, D Campbell, Z Chen, S … - Biochemical Society Transactions, 2003 - bst.portlandpress.com Abbreviations used: AMPK, AMP-activated protein kinase; AMPKK, AMPK kinase;
HMGR, 3-hydroxy-3-methylglutaryl-CoA reductase; GBD, glycogen-binding domain;
AICAR, 5-amino-4-imidazolecarboxamide riboside; PFK-2, ... Cited by 216 - Related articles - Cached - BL Direct - All 9 versions
- ►physiology.org K Sakamoto, LJ Goodyear - Journal of Applied Physiology, 2002 - Am Physiological Soc Physical exercise is a significant stimulus for the regulation of multiple
metabolic and transcriptional processes in skeletal muscle. For example,
exercise increases skeletal muscle glucose uptake, and, after exercise, ... Cited by 151 - Related articles - BL Direct - All 3 versions
- ►jbc.org EK Kim, I Miller, S Aja, LE Landree, M Pinn, … - Journal of Biological Chemistry, 2004 - ASBMB Energy homeostasis and feeding are regulated by the central nervous system. C75,
a fatty acid synthase (FAS) inhibitor, causes weight loss and anorexia, implying
a novel central nervous system pathway(s) for sensing energy balance. AMP- ... Cited by 133 - Related articles - BL Direct - All 4 versions
JFP Wojtaszewski, C MacDonald, JN Nielsen, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc The metabolic role of 5'AMP-activated protein kinase (AMPK) in regulation of
skeletal muscle metabolism in humans is unresolved. We measured isoform-specific
AMPK activity and -acetyl-CoA carboxylase (ACC ) Ser 221 phosphorylation ... Cited by 115 - Related articles - BL Direct - All 4 versions
Y Xing, N Musi, N Fujii, L Zou, I Luptak, MF … - Journal of Biological Chemistry, 2003 - ASBMB AMP-activated protein kinase (AMPK) is an energy-sensing enzyme that plays a
pivotal role in regulating cellular metabolism for sustaining energy homeostasis
under stress conditions. Activation of AMPK has been observed in the heart ... Cited by 113 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org ZP Chen, TJ Stephens, S Murthy, BJ Canny, … - Diabetes, 2003 - Am Diabetes Assoc The effect of exercise intensity on skeletal muscle AMP-activated protein kinase
(AMPK) signaling and substrate metabolism was examined in eight men cycling for
20 min at each of three sequential intensities: low (40 ± 2% VO 2 peak), ... Cited by 103 - Related articles - BL Direct - All 4 versions
- ►physiology.org N Jessen, LJ Goodyear - Journal of Applied Physiology, 2005 - Am Physiological Soc Contracting skeletal muscles acutely increases glucose transport in both healthy
individuals and in people with Type 2 diabetes, and regular physical exercise is
a cornerstone in the treatment of the disease. Glucose transport in ... Cited by 94 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org HA Koistinen, D Galuska, AV Chibalin, J … - Diabetes, 2003 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) activation by AICAR (5-amino-imidazole
carboxamide riboside) is correlated with increased glucose transport in rodent
skeletal muscle via an insulin-independent pathway. We determined in vitro ... Cited by 95 - Related articles - BL Direct - All 7 versions
