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Scholar Results 1 - 6 of 6 citing Whalen: BB rat thymocytes cultured in the presence of islets lose their ability to transfer.... (0.07 sec) 

The insulin gene in diabetes


A Pugliese, D Miceli - Diabetes/Metabolism Reviews - interscience.wiley.com
Lack of insulin production or abnormalities affecting insulin secretion are key
to the development of almost all forms of diabetes, including the common type 1
(insulin-dependent) and type 2 (non-insulin-dependent) diabetes and the ...
Cited by 43 - Related articles - BL Direct - All 3 versions

The iddm4 locus segregates with diabetes susceptibility in congenic WF. iddm4 rats


JP Mordes, J Leif, S Novak, C DeScipio, DL … - Diabetes, 2002 - Am Diabetes Assoc
Viral antibody–free BBDR and WF rats never develop spontaneous diabetes. BBDR
rats, however, develop autoimmune diabetes after perturbation of the immune
system, eg, by viral infection. We previously identified a disease- ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ …


BJ Whalen, J Marounek, JP Mordes, AA … - Journal of Autoimmunity, 2003 - Elsevier
Peripheral T cells can be polarized towards type 1 or type 2 cytokine immune
responses during TCR engagement. Because T cell selection by peptide plus
self-MHC in the thymus requires TCR engagement, we hypothesized that type 1 ...
Cited by 5 - Related articles - BL Direct - All 3 versions

[PDF] Temporary, but Essential Requirement of CD8 T Cells Early in the Pathogenesis of …


H Groen, F Klatter, J Pater, P Nieuwenhuis, J … - Clinical & Developmental Immunology, 2003 - hindawi.com
The Netherlands Autoimmunity-prone BB rats demonstrate a T lymphocytopenia and
abnormal T cell subset distribution. To test whether the life span of all T
cells or only of certain subsets is reduced in BB rats, we thymectomised ...
Cited by 3 - Related articles - View as HTML - BL Direct - All 11 versions

Animal Models of Type 1 Diabetes


J Lang, D Bellgrau - Immunology of type 1 diabetes, 2004 - books.google.com
CHAPTER 3 Animal Models of Type 1 Diabetes: Genetics and Immunological Function
Julie Lang and Donald Bellgrau The ancient Egyptians described diabetes several
millennia ago, but the first major break through in the understanding of ...
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Type 1 Diabetes Mellitus of Man


A Pugliese, GS Eisenbarth - Immunology of type 1 diabetes, 2004 - books.google.com
CHAPTER 7 Type 1 Diabetes Mellitus of Man: Genetic Susceptibility and Resistance
Alberto Pugliese and George S. Eisenbarth Introduction Insulin-dependent
diabetes mellitus (IDDM), or type 1 diabetes, is usually a chronic disease ...
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