Y Wang, G Hallden, R Hill, A Anand, TC Liu, J … - Nature biotechnology, 2003 - nature.com Oncolytic replication-selective adenoviruses constitute a rapidly growing
therapeutic platform for cancer. However, the role of the host immune response
and the E3 immunoregulatory genes of the human adenovirus were unknown ... Cited by 73 - Related articles - BL Direct - All 3 versions
DL Lichtenstein, K Toth, K Doronin, AE … - International reviews of immunology, 2004 - informahealthcare.com In the evolutionary battle between viruses and their hosts, viruses have armed
themselves with weapons to defeat the host's attacks on infected cells. Various
proteins encoded in the adenovirus (Ad) E3 transcription unit protect cells ... Cited by 65 - Related articles - BL Direct - All 7 versions
S Efrat - Trends in molecular medicine, 2002 - Elsevier Replacement of the insulin-producing pancreatic islet β cells represents the
ultimate treatment for type 1 diabetes. Recent advances in islet transplantation
underscore the urgent need for developing alternatives to human tissue ... Cited by 51 - Related articles - All 4 versions
R Bottino, P Lemarchand, M Trucco, N … - Gene Therapy, 2003 - nature.com Type 1 diabetes mellitus, an autoimmune disorder is an attractive candidate for
gene and cell-based therapy. From the use of gene-engineered immune cells to
induce hyporesponsiveness to autoantigens to islet and beta cell surrogate ... Cited by 44 - Related articles - BL Direct - All 4 versions
- ►nih.gov JM Friedman, MS Horwitz - Journal of virology, 2002 - Am Soc Microbiol Recombinant adenoviruses (Ads) are useful tools in gene transfer because they
are able to infect a wide variety of tissues and cell types and do not require a
replicating target cell. However, transgene expression is only transient ... Cited by 43 - Related articles - BL Direct - All 7 versions
MS Horwitz - Journal of Gene Medicine, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 37 - Related articles - BL Direct - All 2 versions
- ►jimmunol.org MMW Chong, Y Chen, R Darwiche, NL Dudek, … - The Journal of Immunology, 2004 - Am Assoc Immnol In type 1 diabetes, cytokine action on cells potentially contributes to cell
destruction by direct cytotoxicity, inducing Fas expression, and up-regulating
class I MHC and chemokine expression to increase immune recognition. To ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►nih.gov AM Lesokhin, F Delgado-Lopez, MS Horwitz - The Journal of Virology, 2002 - jvi.highwire.org Adenoviruses (Ad) have a variety of immunoregulatory genes, many of which are
clustered in a 3.5-kb segment of DNA known as early region 3 (E3). Ad E3 codes
for proteins that downregulate surface expression of class I major ... Cited by 22 - Related articles - BL Direct - All 6 versions
SP Fessler, F Delgado-Lopez, MS Horwitz - Recent progress in multivariate approximation: 4th …, 2001 - books.google.com Mechanisms of E3 Modulation of Immune and Inflammatory Responses SP Fessler•
F. Delgado-Lopez• MS Horwitz Department of Microbiology and Immunology, Albert
Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York, NY ... Cited by 19 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org MA Pierce, HD Chapman, CM Post, A Svetlanov … - Diabetes, 2003 - Am Diabetes Assoc Genes in the early region 3 (E3) of the adenovirus genome allow the virus to
evade host immune responses by interfering with major histocompatibility (MHC)
class I-mediated antigen presentation and tumor necrosis factor- (TNF- )- ... Cited by 18 - Related articles - BL Direct - All 5 versions
