R Lupi, F Dotta, L Marselli, S Del Guerra, M … - Diabetes, 2002 - Am Diabetes Assoc In an effort to better understand the phenomenon of lipotoxicity in human
β-cells, we evaluated the effects of 48-h preculture with 1.0 or 2.0 mmol/l
free fatty acid (FFA) (2:1 oleate to palmitate) on the function and ... Cited by 268 - Related articles - BL Direct - All 7 versions
- ►nih.gov JD Johnson, S Misler - Proceedings of the National Academy of Sciences of …, 2002 - National Acad Sciences Recent studies suggest a role for autocrine insulin signaling in beta cells, but
the mechanism and function of insulin-stimulated Ca 2+ signals is
uncharacterized. We examined Ca 2+ -dependent insulin signaling in human ... Cited by 73 - Related articles - BL Direct - All 11 versions
- ►hematologylibrary.org L Frasca, G Fedele, S Deaglio, C Capuano, R … - Blood, 2006 - bloodjournal.hematologylibrary.org CD38, an ectoenzyme and a signaling receptor, is a novel marker of human mature
monocyte-derived dendritic cells (MDDCs). The working hypothesis is that CD38 is
not only a marker but also contributes to functions specifically gained by ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org A Antonelli, C Ferri, P Fallahi, M Sebastiani, C … - Rheumatology, 2004 - Br Soc Rheumatology Objectives. Mixed cryoglobulinaemia (MC) is a systemic vasculitis frequently
associated with hepatitis C virus (HCV) infection. A possible link between HCV
infection and type 2 diabetes has been suggested. This study evaluated the ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] A Antonelli, P Fallahi, C Nesti, C Pupilli, P … - Clin Exp Immunol, 2001 - pubmedcentral.nih.gov SUMMARY Autoantibodies directed against human CD38 (an enzyme catalysing the
interconversion of NAD1 and cyclic ADP-ribose) have been demonstrated recently
in patients with type 2 diabetes. We tested 220 consecutive Caucasian ... Cited by 28 - Related articles - View as HTML - BL Direct - All 6 versions
A Antonelli, T Tuomi, M Nannipieri, P Fallahi, … - Diabetologia, 2002 - Springer Aims/hypothesis. Autoantibodies against CD38 have been found in some patients
with Type II (non-insulin- dependent) diabetes mellitus and have been shown to
stimulate insulin secretion by cultured human islets. We tested whether ... Cited by 27 - Related articles - BL Direct - All 4 versions
- ►fasebj.org LI SUN, J IQBAL, S DOLGILEVICH, T YUEN, … - The FASEB Journal, 2003 - FASEB We have evaluated the role of the ADP-ribosyl cyclase, CD38, in bone remodeling,
a process by which the skeleton is being renewed constantly through the
coordinated activity of osteoclasts and osteoblasts. CD38 catalyzes the ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►physiology.org F Malavasi, S Deaglio, A Funaro, E Ferrero, AL … - Physiological reviews, 2008 - Am Physiological Soc The membrane proteins CD38 and CD157 belong to an evolutionarily conserved
family of enzymes that play crucial roles in human physiology. Expressed in
distinct patterns in most tissues, CD38 (and CD157) cleaves NAD + and NADP ... Cited by 24 - Related articles - All 3 versions
S Takasawa, H Okamoto - International journal of experimental diabetes research, 2002 - pubmedcentral.nih.gov In the early 1980s, we proposed a unifying model for β-cell damage (The OKAMOTO
model), in which poly(ADP-ribose) synthetase/ polymerase (PARP) activation plays
an essential role in the consumption of NAD + , which leads to energy ... Cited by 15 - Related articles - All 6 versions
R Mallone, E Ortolan, S Pinach, M Volante, M … - Diabetologia, 2002 - Springer Aims/hypothesis. Serum anti-CD38 autoantibodies (aAbs) have been reported in 17
to 19% of patients with long-standing Type I (insulin-dependent) diabe- tes
mellitus and Type II (non-insulin-dependent) dia- betes mellitus. Whether ... Cited by 14 - Related articles - BL Direct - All 5 versions
