S Bonner-Weir, A Sharma - The Journal of Pathology, 2002 - ingentaconnect.com Diabetes, whether type 1 (autoimmune), type 2 or MODY (monogeneic disease due to
mutation of either a key transcription factor or the key enzyme glucokinase), is
a disease due to an inadequate mass of functional pancreatic b cells. ... Cited by 203 - Related articles - BL Direct - All 6 versions
- ►shouxi.net RP Robertson - The New England journal of medicine, 2004 - nejm.highwire.org In 1993 the Diabetes Control and Complications Trial (DCCT) established the
modern standard of care for the medical management of type 1 diabetes mellitus.
1 The DCCT randomly assigned 1441 patients to conventional or intensive ... Cited by 174 - Related articles - All 9 versions
- ►diabetesjournals.org AB Adams, N Shirasugi, MM Durham, E … - Diabetes, 2002 - Am Diabetes Assoc Recent success using a steroid-free immunosuppressive regimen has renewed
enthusiasm for the use of islet transplantation to treat diabetes. Toxicities
associated with the continued use of a calcineurin inhibitor may limit the ... Cited by 98 - Related articles - BL Direct - All 4 versions
RY Calne - International immunopharmacology, 2005 - Elsevier This is a short review of tolerance from the point of view of the clinician.
Various examples of tolerance occurring in patients and animal models that
relate to the clinical experience are described. It is suggested that there ... Cited by 47 - Related articles - BL Direct - All 9 versions
AD Kirk - Immunological reviews, 2003 - prsjournal.com Many methods for reducing the immunosuppressive requirements of
allotransplantation have been proposed based on a growing understanding of
physiological and allospecific immunity. As these regimens are developed ... Cited by 49 - Related articles - Cached - BL Direct - All 6 versions
JH Woo, YY Liu, A Mathias, S Stavrou, Z … - Protein expression and purification, 2002 - Elsevier The bivalent anti-human anti-T cell immunotoxin A-dmDT390-bisFv(G 4 S) was
developed for treatment of T cell leukemia, autoimmune diseases, and tolerance
induction for transplantation. The multi-domain structure of the bivalent ... Cited by 39 - Related articles - BL Direct - All 5 versions
LS Kean, S Gangappa, TC Pearson, CP … - American Journal of Transplantation, 2006 - prsjournal.net Given the significant morbidity associated with current post-transplant
immunosuppressive regimens, induction of immune tolerance continues to be an
important goal of clinical organ transplantation. While many strategies for ... Cited by 41 - Related articles - Cached - BL Direct - All 5 versions
- ►jimmunol.org O Bestard, JM Cruzado, M Mestre, A Caldes, J … - The Journal of Immunology, 2007 - Am Assoc Immnol Exploring new immunosuppressive strategies inducing donor-specific
hyporesponsiveness is an important challenge in transplantation. For this
purpose, a careful immune monitoring and graft histology assessment is ... Cited by 39 - Related articles - All 3 versions
