- ►endojournals.org I Maestre, J Jordan, S Calvo, JA Reig, V Cena … - Endocrinology, 2003 - Endocrine Soc The potential toxic effects of high extracellular concentrations of fatty acids
were tested in ß(INS-1)-cells cultured in the absence of serum, a condition
known to alter cell survival in various systems. This may in part mimic the ... Cited by 82 - Related articles - BL Direct - All 8 versions
- ►rupress.org MA Rizzo, DW Piston - Journal of Cell Biology, 2003 - jcb.rupress.org Glucokinase (GK) activity plays a key role in glucose-stimulated insulin
secretion from pancreatic ß cells. Insulin regulates GK activity by modulating
its association with secretory granules, although little is known about the ... Cited by 50 - Related articles - BL Direct - All 10 versions
SR Smukler, L Tang, MB Wheeler, AMF … - Diabetes, 2002 - Am Diabetes Assoc The role nitric oxide (NO) plays in physiological insulin secretion has been
controversial. Here we present evidence that exogenous NO stimulates insulin
secretion, and that endogenous NO production occurs and is involved in the ... Cited by 49 - Related articles - BL Direct - All 7 versions
A Giordano, C Tonello, A Bulbarelli, V Cozzi, … - FEBS letters, 2002 - Elsevier The intracellular localization and activity of the nitric oxide synthase (NOS)
isoforms were investigated in rat brown adipocytes. Immunohistochemistry showed
cytoplasmic and nuclear staining for the endothelial NOS (eNOS) and ... Cited by 46 - Related articles - All 5 versions
- ►diabetesjournals.org LJC van Loon, M Kruijshoop, PPCA … - Diabetes Care, 2003 - Am Diabetes Assoc OBJECTIVE—Insulin secretion in response to carbohydrate intake is blunted in
type 2 diabetic patients. However, it is not clear whether the insulin response
to other stimuli, such as amino acids, is also diminished. Recently, we ... Cited by 39 - Related articles - BL Direct - All 6 versions
- ►physiology.org R Henningsson, A Salehi, I Lundquist - American Journal of Physiology- Cell Physiology, 2002 - Am Physiological Soc The role of islet constitutive nitric oxide synthase (cNOS) in insulin-releasing
mechanisms is controversial. By measuring enzyme activities and protein
expression of NOS isoforms [ie, cNOS and inducible NOS (iNOS)] in islets of ... Cited by 39 - Related articles - BL Direct - All 5 versions
SM de la Monte, JR Wands - Journal of Alzheimer's Disease, 2006 - IOS Press Abstract. Glucose uptake and energy metabolism in the brain are regulated by
insulin and insulin-like growth factors (IGF). Recent studies demonstrated
progressive deficiencies in brain insulin and IGF production and ... Cited by 33 - Related articles - BL Direct - All 2 versions
SS Qader, I Lundquist, M Ekelund, R … - Regulatory peptides, 2005 - Elsevier In view of our previous data, showing that ghrelin and nitric oxide (NO) display
apparently parallel effects on insulin secretion (inhibitory) and glucagon
secretion (stimulatory), we have now investigated the effect of ghrelin on ... Cited by 31 - Related articles - All 3 versions
- ►physiology.org I Lundquist, P Alm, A Salehi, R Henningsson, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc A key question for understanding the mechanisms of pulsatile insulin release is
how the underlying -cell oscillations of the cytoplasmic Ca 2+ concentration
([Ca 2+ ] i ) are synchronized within and among the islets in the pancreas. ... Cited by 30 - Related articles - BL Direct - All 3 versions
- ►physiology.org Y Kaneko, T Ishikawa, S Amano, K Nakayama - American Journal of Physiology- Cell Physiology, 2003 - Am Physiological Soc In isolated rat pancreatic -cells, the nitric oxide (NO) donor NOC-7 at 1 µM
reduced the amplitude of the oscillations of cytosolic Ca 2+ concentration ([Ca
2+ ] c ) induced by 11.1 mM glucose, and at 10 µM terminated them. In the ... Cited by 25 - Related articles - BL Direct - All 4 versions
