CS Stump, KR Short, ML Bigelow, JM Schimke … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences Mitochondria are the primary site of skeletal muscle fuel metabolism and ATP
production. Although insulin is a major regulator of fuel metabolism, its effect
on mitochondrial ATP production is not known. Here we report increases in ... Cited by 135 - Related articles - BL Direct - All 10 versions
Y Kamei, S Miura, M Suzuki, Y Kai, J Mizukami … - Journal of Biological Chemistry, 2004 - ASBMB FOXO1, a member of the FOXO forkhead type transcription factors, is markedly
up-regulated in skeletal muscle in energy-deprived states such as fasting and
severe diabetes, but its functions in skeletal muscle have remained poorly ... Cited by 117 - Related articles - BL Direct - All 4 versions
K Højlund, K Wrzesinski, PM Larsen, SJ Fey, … - Journal of Biological Chemistry, 2003 - ASBMB Insulin resistance in skeletal muscle is a hallmark feature of type 2 diabetes.
An increasing number of enzymes and metabolic pathways have been implicated in
the development of insulin resistance. However, the primary cellular cause ... Cited by 94 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org A Kautzky-Willer, M Krssak, C Winzer, G … - Diabetes, 2003 - Am Diabetes Assoc Women with previous gestational diabetes (pGDM) are frequently
insulin-resistant, which could relate to intramyocellular lipid content (IMCL).
IMCL were measured with 1 H nuclear magnetic resonance spectroscopy in ... Cited by 69 - Related articles - BL Direct - All 6 versions
A Rudich, D Konrad, D Török, R Ben-Romano, … - Diabetologia, 2003 - Springer Aims/hypothesis. Insulin-dependent glucose influx in skeletal muscle and
adipocytes is believed to rely largely on GLUT4, but this has not been confirmed
di- rectly. We assessed the relative functional contribution of GLUT4 in ... Cited by 56 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org S Rice, N Christoforidis, C Gadd, D Nikolaou … - Human Reproduction, 2005 - ESHRE BACKGROUND: Insulin resistance and hyperinsulinaemia are well-recognized
characteristics of anovulatory women with polycystic ovary syndrome (PCOS) but,
paradoxically, steroidogenesis by PCOS granulosa cells remains responsive ... Cited by 52 - Related articles - All 6 versions
- ►diabetesjournals.org WG Aschenbach, MF Hirshman, N Fujii, K … - Diabetes, 2002 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is proposed to stimulate fat and
carbohydrate catabolism to maintain cellular energy status. Recent studies
demonstrate that pharmacologic activation of AMPK and mutations in the ... Cited by 52 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org M Desrois, RJ Sidell, D Gauguier, LM King, … - Cardiovascular research, 2004 - cardiovascres.oxfordjournals.org Objective: Whole body insulin resistance and diabetes are risk factors for
cardiovascular diseases, yet little is known about insulin resistance in the
diabetic heart. The aim of this work was to define the insulin response in ... Cited by 51 - Related articles - All 8 versions
A Bloch-Damti, N Bashan - Antioxidants & Redox Signaling, 2005 - liebertonline.com T YPE 2 DIABETES MELLITUS (T2DM) represents the final stage of a chronic and
progressive syndrome represent- ing a heterogenous disorder caused by various
combinations of insulin resistance and decreased pancreatic ß-cell func- ... Cited by 45 - Related articles - BL Direct - All 3 versions
LJ Foster, A Rudich, I Talior, N Patel, X … - Journal of proteome research, 2006 - cat.inist.fr The insulin-regulated glucose transporter(GLUT 4) translocates to the plasma
membrane in response to insulin in order to facilitate the postprandial uptake
of glucose into fat and muscle cells. While early insulin receptor ... Cited by 45 - Related articles - All 7 versions
