AJ Sanyal, PS Mofrad, MJ Contos, C Sargeant, … - Clinical Gastroenterology and Hepatology, 2004 - Elsevier Background & Aims: Insulin resistance and oxidative stress contribute to the
pathogenesis of nonalcoholic steatohepatitis (NASH). We conducted a pilot study
for the following reasons: (1) to test the hypothesis that a combination of ... Cited by 182 - Related articles - All 9 versions
- ►jbc.org JA Chavez, TA Knotts, LP Wang, G Li, RT … - Journal of Biological Chemistry, 2003 - ASBMB Multiple studies suggest that lipid oversupply to skeletal muscle contributes to
the development of insulin resistance, perhaps by promoting the accumulation of
lipid metabolites capable of inhibiting signal transduction. Herein we ... Cited by 156 - Related articles - BL Direct - All 5 versions
D Bach, S Pich, FX Soriano, N Vega, B … - Journal of Biological Chemistry, 2003 - ASBMB In many cells and specially in muscle, mitochondria form elongated filaments or
a branched reticulum. We show that Mfn2 (mitofusin 2), a mitochondrial membrane
protein that participates in mitochondrial fusion in mammalian cells, is ... Cited by 147 - Related articles - BL Direct - All 6 versions
- ►fasebj.org [PDF] A Bonen, ML Parolin, GR Steinberg, J Calles … - The FASEB Journal, 2004 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.03-1065fje. Published online
May 7, 2004. Triacylglycerol accumulation in human obesity and type 2 ... Cited by 131 - Related articles - BL Direct - All 7 versions
K Preiss-Landl, R Zimmermann, G Hämmerle, … - Current opinion in lipidology, 2002 - journals.lww.com Purpose of review The aim of this review is to summarize and discuss recent
advances in the understanding of the physiological role of lipoprotein lipase in
lipid and energy metabolism. Recent findings Studies on the transcriptional ... Cited by 117 - Related articles - BL Direct - All 7 versions
BD Hegarty, GJ Cooney, EW Kraegen, SM … - Diabetes, 2002 - Am Diabetes Assoc In humans and animal models, increased lipid content of skeletal muscle is
strongly associated with insulin resistance. However, it is unclear whether this
accumulation is due to increased uptake or reduced utilization of fatty ... Cited by 77 - Related articles - BL Direct - All 5 versions
- ►physiology.org B Kiens - Physiological reviews, 2006 - Am Physiological Soc Lipids as fuel for energy provision originate from different sources:
albumin-bound long-chain fatty acids (LCFA) in the blood plasma, circulating
very-low-density lipoproteins-triacylglycerols (VLDL-TG), fatty acids from ... Cited by 79 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org SLM Coort, DM Hasselbaink, DPY Koonen, J … - Diabetes, 2004 - Am Diabetes Assoc In obesity, the development of cardiomyopathy is associated with the
accumulation of myocardial triacylglycerols (TAGs), possibly stemming from
elevation of myocardial long-chain fatty acid (LCFA) uptake. Because LCFA ... Cited by 64 - Related articles - BL Direct - All 8 versions
- ►shouxi.net N Turner, CR Bruce, SM Beale, KL Hoehn, T … - Diabetes, 2007 - Am Diabetes Assoc A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has
been proposed as a major factor leading to the accumulation of intramuscular
lipids and their subsequent deleterious effects on insulin action. Here, we ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►shouxi.net D Bach, D Naon, S Pich, FX Soriano, N Vega, J … - Diabetes, 2005 - Am Diabetes Assoc The primary gene mutated in Charcot-Marie-Tooth type 2A is mitofusin-2 (Mfn2).
Mfn2 encodes a mitochondrial protein that participates in the maintenance of the
mitochondrial network and that regulates mitochondrial metabolism and ... Cited by 41 - Related articles - BL Direct - All 5 versions
