MA Noor, T Seneviratne, FT Aweeka, JC Lo, JM … - Aids, 2002 - journals.lww.com From the From the Department of a Medicine, University of California, the b Metabolism and Endocrine
Sections, San Francisco Department of Veterans Affairs Medical Center, the Department of c
Pharmacology University of California, the d Division of Endocrinology, San Francisco ... Cited by 224 - Related articles - BL Direct - All 8 versions
- ►hivtri.com [PDF] A Carr - Aids, 2003 - journals.lww.com HIV lipodystrophy is a heterogeneous syndrome, which has yet to be objectively defined, comprising
peripheral lipoatrophy, central fat accumulation and lipomata, along with hyperlipidaemia, insulin
resistance and lactic acidaemia. Both nucleoside analogues and protease inhibitors are ... Cited by 182 - Related articles - BL Direct - All 11 versions
- ►diabetesjournals.org SK Gan, K Samaras, CH Thompson, EW Kraegen, A … - Diabetes, 2002 - Am Diabetes Assoc HIV protease inhibitor-related lipodystrophy is characterized by peripheral fat loss,
hyperlipidemia, and insulin resistance. Increased availability of lipid to muscle may be one of
the mechanisms that induce insulin resistance. Regional fat, intramyocellular lipid (by 1 H- ... Cited by 98 - Related articles - BL Direct - All 4 versions
HJ Woerle, PR Mariuz, C Meyer, RC Reichman, EM … - Diabetes, 2003 - Am Diabetes Assoc The mechanisms responsible for the deterioration in glucose tolerance associated with protease
inhibitor–containing regimens in HIV infection are unclear. Insulin resistance has been implicated
as a major factor, but the affected tissues have not been identified. Furthermore, β-cell ... Cited by 99 - Related articles - BL Direct - All 9 versions
D Nolan, M John, S Mallal - Antiviral therapy(London), 2001 - cat.inist.fr Clinical research has indicated that the use of nucleoside reverse transcriptase
inhibitor(NRTI) and HIV protease inhibitor(PI) therapy is associated with a risk of long-term toxicity
syndromes, and that the aetiopathogenesis of these adverse effects is independent of the ... Cited by 82 - Related articles - BL Direct - All 4 versions
PW Hruz, H Murata, H Qiu, M Mueckler - Diabetes, 2002 - Am Diabetes Assoc The use of HIV protease inhibitors (PIs) has been associated with several metabolic
changes, including lipodystrophy, hyperlipidemia, and insulin resistance. The etiology of these
adverse effects remains unknown. PIs have recently been found to cause acute and ... Cited by 76 - Related articles - BL Direct - All 4 versions
C Huang, R Somwar, N Patel, W Niu, D Török, A Klip - Diabetes, 2002 - Am Diabetes Assoc Hyperglycemia and hyperinsulinemia are cardinal features of acquired insulin resistance. In
adipose cell cultures, high glucose and insulin cause insulin resistance of glucose uptake, but
because of altered GLUT4 expression and contribution of GLUT1 to glucose uptake, the ... Cited by 72 - Related articles - BL Direct - All 5 versions
- ►nih.gov GMN Behrens, AR Boerner, K Weber, J van … - Journal of Clinical …, 2002 - Am Soc Clin Investig Insulin resistance is a frequently observed side effect of highly active antiretroviral therapy
(HAART). Currently, very little is known about the mechanisms or specific tissues involved. We
aimed to identify possible defects in skeletal muscle glucose uptake and metabolism in ... Cited by 68 - Related articles - BL Direct - All 7 versions
- ►endojournals.org D Chen, A Misra, A Garg - Journal of Clinical Endocrinology & …, 2002 - Endocrine Soc Human immunodeficiency virus (HIV) infection is a major global health problem. Recently, combination
therapy including HIV-1 protease inhibitors (PIs) has dramatically improved the long-term survival
of HIV-infected patients. However, such therapy is associated with a lipodystrophy ... Cited by 65 - Related articles - All 5 versions
A Rudich, D Konrad, D Török, R Ben-Romano, C … - Diabetologia, 2003 - Springer Aims/hypothesis. Insulin-dependent glucose influx in skeletal muscle and adipocytes is believed
to rely largely on GLUT4, but this has not been confirmed di- rectly. We assessed the relative
functional contribution of GLUT4 in experimental models of skeletal muscle and ... Cited by 56 - Related articles - BL Direct - All 3 versions
