- ►ahajournals.org C Rask-Madsen, GL King - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc In diabetes and insulin resistance, activation of protein kinase C (PKC) in
vascular cells may be a key link between elevated plasma and tissue
concentrations of glucose and nonesterified fatty acids and abnormal ... Cited by 84 - Related articles - All 9 versions
S Grethe, MPS Ares, T Andersson, MI Pörn- … - Experimental cell research, 2004 - Elsevier The role of p38 mitogen-activated protein kinase (MAPK) in apoptosis is a matter
of debate. Here, we investigated the involvement of p38 MAPK in endothelial
apoptosis induced by tumor necrosis factor α (TNF). We found that ... Cited by 64 - Related articles - All 5 versions
- ►amjpathol.org AB El-Remessy, M Al-Shabrawey, Y Khalifa, NT … - American Journal of Pathology, 2006 - ASIP Diabetic retinopathy is characterized by blood-retinal barrier (BRB) breakdown
and neurotoxicity. These pathologies have been associated with oxidative stress
and proinflammatory cytokines, which may operate by activating their ... Cited by 56 - Related articles - BL Direct - All 11 versions
- ►jbc.org ME McMullen, PW Bryant, CC Glembotski, PA … - Journal of Biological Chemistry, 2005 - ASBMB Pathological conditions such as hypertension and hyperglycemia as well as
abrasions following balloon angioplasty all lead to endothelial dysfunction that
impacts disease morbidity. These conditions are associated with the ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org ML Sheu, FM Ho, RS Yang, KF Chao, WW Lin, … - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc Methods and Results— For detection of apoptosis, the morphological Hoechst
staining and Annexin V/propidium iodide staining were used. Glucose upregulated
COX-2 protein expression, which was associated with the induction of ... Cited by 54 - Related articles - All 6 versions
N Morishita, H Nakagami, R Morishita, S … - Biochemical and Biophysical Research …, 2005 - Elsevier To enter the realm of human gene therapy, a novel drug delivery system is
required for efficient delivery of small molecules with high safety for clinical
usage. We have developed a unique vector “HVJ-E (hemagglutinating virus ... Cited by 51 - Related articles - All 4 versions
- ►biologists.org AB El-Remessy, M Bartoli, DH Platt, D Fulton, … - Journal of cell science, 2005 - jcs.biologists.org In diabetic retinopathy, endothelial cell apoptosis is paradoxically increased
despite upregulation of the potent pro-survival factor VEGF. We tested the
hypothesis that elevated glucose levels disrupt VEGF's pro-survival ... Cited by 51 - Related articles - All 8 versions
BF Liu, S Miyata, Y Hirota, S Higo, H … - Kidney international, 2003 - nature.com The formation of methylglyoxal (MG), a highly reactive dicarbonyl compound, is
accelerated through several pathways, including the glycation reaction under
diabetic conditions, presumably contributing to tissue injury in diabetes. ... Cited by 48 - Related articles - BL Direct - All 4 versions
L Cai, YJ Kang - Cardiovascular Toxicology, 2003 - Springer *Author to whom all correspondence and reprint requests should be addressed:
Drs. L. Cai or Y. James Kang, Department of Medicine, University of Louisville
School of Medicine, Louisville, KY 40202. E-mail: L0cai001@ ... Cited by 43 - Related articles - All 3 versions
DJ Jiang, SJ Jia, Z Dai, YJ Li - Journal of molecular and cellular cardiology, 2006 - Elsevier Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide
synthase (NOS), is emerging as a key contributor for endothelial dysfunction and
its effects on endothelium are not yet completely defined. The aim of this ... Cited by 38 - Related articles - All 5 versions