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Scholar Results 1 - 10 of about 61 citing Nakagami: Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3.... (0.16 sec) 

Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance

- ahajournals.org
C Rask-Madsen, GL King - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc
In diabetes and insulin resistance, activation of protein kinase C (PKC) in
vascular cells may be a key link between elevated plasma and tissue
concentrations of glucose and nonesterified fatty acids and abnormal ...
Cited by 84 - Related articles - All 9 versions

p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and …


S Grethe, MPS Ares, T Andersson, MI Pörn- … - Experimental cell research, 2004 - Elsevier
The role of p38 mitogen-activated protein kinase (MAPK) in apoptosis is a matter
of debate. Here, we investigated the involvement of p38 MAPK in endothelial
apoptosis induced by tumor necrosis factor α (TNF). We found that ...
Cited by 64 - Related articles - All 5 versions

Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental …

- amjpathol.org
AB El-Remessy, M Al-Shabrawey, Y Khalifa, NT … - American Journal of Pathology, 2006 - ASIP
Diabetic retinopathy is characterized by blood-retinal barrier (BRB) breakdown
and neurotoxicity. These pathologies have been associated with oxidative stress
and proinflammatory cytokines, which may operate by activating their ...
Cited by 56 - Related articles - BL Direct - All 11 versions

Activation of p38 has opposing effects on the proliferation and migration of endothelial cells

- jbc.org
ME McMullen, PW Bryant, CC Glembotski, PA … - Journal of Biological Chemistry, 2005 - ASBMB
Pathological conditions such as hypertension and hyperglycemia as well as
abrasions following balloon angioplasty all lead to endothelial dysfunction that
impacts disease morbidity. These conditions are associated with the ...
Cited by 56 - Related articles - BL Direct - All 5 versions

High glucose induces human endothelial cell apoptosis through a phosphoinositide 3- …

- ahajournals.org
ML Sheu, FM Ho, RS Yang, KF Chao, WW Lin, … - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc
Methods and Results— For detection of apoptosis, the morphological Hoechst
staining and Annexin V/propidium iodide staining were used. Glucose upregulated
COX-2 protein expression, which was associated with the induction of ...
Cited by 54 - Related articles - All 6 versions

Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector


N Morishita, H Nakagami, R Morishita, S … - Biochemical and Biophysical Research …, 2005 - Elsevier
To enter the realm of human gene therapy, a novel drug delivery system is
required for efficient delivery of small molecules with high safety for clinical
usage. We have developed a unique vector “HVJ-E (hemagglutinating virus ...
Cited by 51 - Related articles - All 4 versions

Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3- …

- biologists.org
AB El-Remessy, M Bartoli, DH Platt, D Fulton, … - Journal of cell science, 2005 - jcs.biologists.org
In diabetic retinopathy, endothelial cell apoptosis is paradoxically increased
despite upregulation of the potent pro-survival factor VEGF. We tested the
hypothesis that elevated glucose levels disrupt VEGF's pro-survival ...
Cited by 51 - Related articles - All 8 versions

Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase …


BF Liu, S Miyata, Y Hirota, S Higo, H … - Kidney international, 2003 - nature.com
The formation of methylglyoxal (MG), a highly reactive dicarbonyl compound, is
accelerated through several pathways, including the glycation reaction under
diabetic conditions, presumably contributing to tissue injury in diabetes. ...
Cited by 48 - Related articles - BL Direct - All 4 versions

Cell death and diabetic cardiomyopathy


L Cai, YJ Kang - Cardiovascular Toxicology, 2003 - Springer
*Author to whom all correspondence and reprint requests should be addressed:
Drs. L. Cai or Y. James Kang, Department of Medicine, University of Louisville
School of Medicine, Louisville, KY 40202. E-mail: L0cai001@ ...
Cited by 43 - Related articles - All 3 versions

Asymmetric dimethylarginine induces apoptosis via p38 MAPK/caspase-3-dependent …


DJ Jiang, SJ Jia, Z Dai, YJ Li - Journal of molecular and cellular cardiology, 2006 - Elsevier
Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide
synthase (NOS), is emerging as a key contributor for endothelial dysfunction and
its effects on endothelium are not yet completely defined. The aim of this ...
Cited by 38 - Related articles - All 5 versions


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