- ►oxfordjournals.org M Mazzali, T Kipari, V Ophascharoensuk, JA … - Qjm, 2002 - Oxford Univ Press Osteopontin (OPN) is a multifunctional protein, and although highly expressed in
bone, it is also expressed by various cell types including macrophages,
endothelial cells, smooth muscle cells and epithelial cells. 1, 2 OPN is ... Cited by 133 - Related articles - BL Direct - All 3 versions
- ►elsevier.com SM Evans, CJ Koch - Cancer letters, 2003 - Elsevier Low tissue oxygen concentration has been shown to be important in the response
of human tumors to radiation therapy, chemotherapy and other treatment
modalities. Hypoxia is also known to be a prognostic indicator, as hypoxic ... Cited by 116 - Related articles - All 10 versions
- ►physiology.org A Sahai, P Malladi, X Pan, R Paul, H Melin- … - American Journal of Physiology- Gastrointestinal and …, 2004 - Am Physiological Soc Obesity and type 2 diabetes are associated with nonalcoholic steatohepatitis
(NASH), but an obese/diabetic animal model that mimics human NASH remains
undefined. We examined the induction of steatohepatitis and liver fibrosis ... Cited by 77 - Related articles - BL Direct - All 4 versions
SM Evans, KD Judy, I Dunphy, WT Jenkins, WT … - Clinical cancer research, 2004 - AACR We investigated whether increasing levels of tissue hypoxia, measured by the
binding of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)
acetamide] or by Eppendorf needle electrodes, were associated with tumor ... Cited by 55 - Related articles - All 5 versions
- ►physiology.org A Sahai, P Malladi, H Melin-Aldana, RM Green … - American Journal of Physiology- Gastrointestinal and …, 2004 - Am Physiological Soc The pathogenesis of nonalcoholic steatohepatitis (NASH) is poorly defined.
Feeding mice a diet deficient in methionine and choline (MCD diet) induces
experimental NASH. Osteopontin (OPN) is a Th1 cytokine that plays an ... Cited by 50 - Related articles - All 5 versions
NX Chen, SM Moe - Current Diabetes Reports, 2003 - Springer Introduction Diabetes mellitus is one of the more common diseases in the world,
found in as many as 17 million people in the United States, or 6.2% of the
population [1]. In addition, the prevalence is increasing, particularly in ... Cited by 47 - Related articles - BL Direct - All 2 versions
JR White, RA Harris, SR Lee, MH Craigon, K … - Genomics, 2004 - Elsevier The cellular response to hypoxia involves the promotion of angiogenesis, leading
to increased blood flow and oxygenation. The macrophage has been identified as
an orchestrator of this response in several pathologies, through the ... Cited by 47 - Related articles - All 5 versions
E Potier, E Ferreira, R Andriamanalijaona, JP … - Bone, 2007 - Elsevier Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been
proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded
in vitro in 21% O 2 ) undergo temporary oxygen deprivation due to the lack ... Cited by 42 - Related articles - All 33 versions
- ►physiology.org CP Sodhi, YS Kanwar, A Sahai - American Journal of Physiology- Heart and Circulatory …, 2003 - Am Physiological Soc We examined the effect of hypoxia and high glucose (HG) on ANG II type 1 (AT 1 )
receptor expression and proliferation in cultured vascular smooth muscle (VSM)
cells. Exposure of quiescent cells to hypoxia in a serum-free DME-Ham's ... Cited by 40 - Related articles - BL Direct - All 4 versions