- ►stuba.sk [PDF] M Valko, D Leibfritz, J Moncol, MTD Cronin, M … - International Journal of …, 2007 - Elsevier Reactive oxygen species (ROS) and reactive nitrogen species (RNS, eg nitric oxide, NO ) are
well recognised for playing a dual role as both deleterious and beneficial species. ROS and
RNS are normally generated by tightly regulated enzymes, such as NO synthase (NOS) ... Cited by 695 - Related articles - All 9 versions
S Yamagishi, Y Inagaki, T Okamoto, S Amano, K … - Journal of Biological …, 2002 - ASBMB Advanced glycation end products (AGE) have been implicated in the pathogenesis of glomerulosclerosis
in diabetes. However, their involvement in the development of the early phase of diabetic nephropathy
has not been fully elucidated. We investigated the effects of AGE on growth and on ... Cited by 161 - Related articles - BL Direct - All 6 versions
JE Gerich - Archives of Internal Medicine, 2003 - archinte.highwire.org It is well established that strict glycemic control (hemoglobin A 1c <7.0%) can prevent the microvascular
complications of diabetes mellitus. Recent studies indicate that elevated plasma glucose concentrations
are an independent and clinically significant risk factor for cardiovascular disease in ... Cited by 135 - Related articles - BL Direct - All 5 versions
D Bonnefont-Rousselot - Current Opinion in Clinical Nutrition & …, 2002 - journals.lww.com Purpose of review This review aims at presenting new concepts of glucose- induced damage
in diabetes via an increased production of oxygen free radicals. Recent findings Reactive oxygen
species modulate various biological functions by stimulating transduction signals, some ... Cited by 132 - Related articles - BL Direct - All 4 versions
S Yamagishi, T Imaizumi - Current pharmaceutical design, 2005 - ingentaconnect.com Abstract: Diabetic vascular complication is a leading cause of end-stage renal failure, acquired
blindness, a variety of neuropathies and accelerated atherosclerosis, which could account for
disabilities and high mortality rates in patients with diabetes. Recent large prospective ... Cited by 123 - Related articles - All 3 versions
L Cai, YJ Kang - Cardiovascular Toxicology, 2001 - Springer *Author to whom all correspondence and reprint requests should be addressed: Y. James
Kang, Department of Medicine, University of Louisville School of Medicine, 511 S. Floyd St., MDR
530, Louisville, KY 40202. E-mail: yjkang01@athena. louisville.edu Cardiovascular ... Cited by 109 - Related articles - All 3 versions
- ►jbc.org Y Gorin, K Block, J Hernandez, B Bhandari, B … - Journal of Biological …, 2005 - ASBMB Renal hypertrophy and extracellular matrix accumulation are early features of diabetic
nephropathy. We investigated the role of the NAD(P)H oxidase Nox4 in generation of reactive
oxygen species (ROS), hypertrophy, and fibronectin expression in a rat model of type 1 ... Cited by 93 - Related articles - BL Direct - All 5 versions
MM Spitaler, WF Graier - Diabetologia, 2002 - Springer There is overwhelming evidence for an involvement of reactive oxygen species (ROS) in the
pathogenesis of diabetes-associated vascular complications. How- ever, neither the exact source
of the ROS initiating cascades leading to cell dysfunction in diabetes nor their chemical ... Cited by 89 - Related articles - BL Direct - All 7 versions
S Yamagishi, Y Inagaki, S Amano, T Okamoto, M … - … and biophysical research …, 2002 - Elsevier Pigment epithelium-derived factor (PEDF) has recently been shown to be the most potent inhibitor
of angiogenesis in the mammalian eye, suggesting that loss of PEDF is involved in the pathogenesis
of proliferative diabetic retinopathy. However, a protective role for PEDF in pericyte loss in ... Cited by 89 - Related articles - BL Direct - All 9 versions
AEL Midaoui, A Elimadi, L Wu, PS Haddad, J de … - American Journal of …, 2003 - Elsevier Chronic administration of glucose resulted in a 29% increase in blood pressure, 30% increase
in glycemia, 286% increase in insulinemia, and 408% increase in insulin resistance index. Chronic
glucose feeding also resulted in a 22% greater mitochondrial superoxide anion ... Cited by 84 - Related articles - All 6 versions
