AE Morelli, AW Thomson - Immunological reviews, 2003 - interscience.wiley.com Summary: Dendritic cells (DCs) are uniquely well-equipped antigen-presenting cells (APCs) regarded
classically as sentinels of the immune response, which induce and regulate T-cell reactivity. They
play critical roles in central ... Cited by 195 - Related articles - BL Direct - All 7 versions
AE Morelli, H Hackstein, AW Thomson - Seminars in Immunology, 2001 - Elsevier Dendritic cells (DC) are professional antigen (Ag)-presenting cells considered traditionally as the
passenger leukocytes that, after migration from transplanted tissues, stimulate allospecific naive T
cell responses and trigger acute ... Cited by 76 - Related articles - BL Direct - All 3 versions
T Taner, H Hackstein, Z Wang, AE Morelli, … - American Journal of …, 2005 - interscience.wiley.com Tolerogenic properties of dendritic cells (DC), particularly those in the immature state, and their
therapeutic potential are increasingly being recognized. Among several distinct approaches to
generate stably immature DC, ... Cited by 72 - Related articles - All 4 versions
- ►highwire.org AM Woltman, C van Kooten - Journal of leukocyte biology, 2003 - jleuk.highwire.org In recent years, dendritic cells (DCs) have entered the center court of immune regulation. Dependent
on their ontogeny, state of differentiation, and maturation and thereby a variable expression of
membrane-bound and soluble ... Cited by 52 - Related articles - BL Direct - All 5 versions
T Kawai, H Sogawa, S Boskovic, G … - American Journal of …, 2004 - interscience.wiley.com Costimulatory blockade with anti-CD154 monoclonal antibody (aCD154) prolongs allograft survival in
nonhuman primates, but has not reliably induced tolerance when used alone. In the current studies,
we evaluated the effect of adding ... Cited by 44 - Related articles - BL Direct - All 3 versions
- ►aspetjournals.org AS Narang, RI Mahato - Pharmacological reviews, 2006 - ASPET Islet transplantation may be used to treat type I diabetes. Despite tremendous progress in islet
isolation, culture, and preservation, the clinical use of this modality of treatment is limited due
to post-transplantation challenges ... Cited by 32 - Related articles - BL Direct - All 13 versions
G Raimondi, AW Thomson - Contributions to nephrology, 2005 - content.karger.com Abstract Donor dendritic cells (DCs) and those of host origin play key roles in the instigation and
maintenance of immune responses to organ allografts. In the normal steady state, however, DCs are
important for the maintenance of ... Cited by 30 - Related articles - BL Direct - All 5 versions
SF Oluwole, OO Oluwole, HA DePaz, AO Adeyeri, P … - Transplant Immunology, 2003 - Elsevier The Holy Grail of clinical organ transplantation is the safe induction of allograft tolerance.
Transplant tolerance has been successfully induced in animal models. Since T cells play a pivotal
role in graft rejection, modulating ... Cited by 19 - Related articles - All 3 versions
M Nouri-Shirazi, AW Thomson - Expert Opin. Biol. Ther., 2006 - informahealthcare.com Dendritic cells (DCs) play a crucial role during the initiation of immune responses against non-self
antigens. Following organ transplantation, activated donor- and recipient-derived DCs participate
actively in graft rejection by ... Cited by 17 - Related articles - BL Direct - All 5 versions
