JS Wadia, SF Dowdy - Current opinion in biotechnology, 2002 - Elsevier Currently, the ability to ectopically express novel proteins that can either
alter the cellular phenotype or provide therapeutic benefit is largely limited
to recombinant genetic approaches. The introduction of the transgene and ... Cited by 232 - Related articles - BL Direct - All 6 versions
GPH Dietz, M Bδhr - Molecular and Cellular Neuroscience, 2004 - Elsevier In recent years, vast amounts of data on the mechanisms of neural de- and
regeneration have accumulated. However, only in disproportionally few cases has
this led to efficient therapies for human patients. Part of the problem is ... Cited by 198 - Related articles - All 3 versions
B Gupta, TS Levchenko, VP Torchilin - Advanced drug delivery reviews, 2005 - Elsevier Cell-penetrating peptides (CPPs) have been used to overcome the lipophilic
barrier of the cellular membranes and deliver large molecules and even small
particles inside the cell for their biological actions. CPPs are being used ... Cited by 174 - Related articles - All 5 versions
MA Lindsay - Current Opinion in Pharmacology, 2002 - Elsevier The complexity of biological interactions makes it increasingly difficult to
predict gene and protein function as you proceed from the immediate metabolic
pathway to the cellular and animal level. This phenomenon is partially ... Cited by 113 - Related articles - All 3 versions
EL Snyder, SF Dowdy - Pharmaceutical research, 2004 - Springer Received November 7, 2003; accepted November 10, 2003 Protein transduction
domains (PTDs) are small cationic peptides that can facilitate the uptake of
large, biologically active molecules into mammalian cells. Recent reports ... Cited by 103 - Related articles - BL Direct - All 4 versions
C Ricordi - Diabetes, 2003 - medscape.com It has indeed been a distinct honor to be the recipient of the 2002 Outstanding
Scientific Achievement Award, and I was happy to accept it, on behalf of the
entire islet transplant field, as there have been many surgeons, ... Cited by 100 - Related articles - All 8 versions
C Brigati, M Giacca, DM Noonan, A Albini - FEMS microbiology letters, 2003 - interscience.wiley.com The human immunodeficiency virus (HIV-1) (transactivator of transcription (Tat))
protein is a pleiotropic factor that induces a broad range of biological effects
in numerous cell types. At the HIV promoter, Tat is a powerful ... Cited by 68 - Related articles - All 3 versions
KK Rehman, S Bertera, R Bottino, AN … - Journal of Biological Chemistry, 2003 - ASBMB We have previously demonstrated that adenoviral gene transfer of the NF-κB
inhibitor IκB to human islets results in protection from interleukin
(IL)-1β-mediated dysfunction and apoptosis. Here we report that human and ... Cited by 53 - Related articles - BL Direct - All 4 versions
H Noguchi, S Matsumoto - Acta Medica Okayama, 2006 - lib.okayama-u.ac.jp The direct intracellular delivery of proteins has, until recently, been
difficult to achieve, due primar- ily to the bioavailability barrier of the
plasma membrane. During the past 15 years, a variety of peptides called ... Cited by 49 - Related articles - View as HTML - BL Direct - All 8 versions
