Y Dor, J Brown, OI Martinez, DA Melton - Nature, 2004 - molecool.wustl.edu How tissues generate and maintain the correct number of cells is a fundamental problem in
biology. In principle, tissue turnover can occur by the differentiation of stem cells, as is well documented
for blood, skin and intestine, or by the duplication of existing differentiated cells. Recent ... Cited by 792 - Related articles - View as HTML - BL Direct - All 26 versions
- ►physiology.org L Bouwens, I Rooman - Physiological reviews, 2005 - Am Physiological Soc Beta-cell mass regulation represents a critical issue for understanding diabetes, a disease characterized
by a near-absolute (type 1) or relative (type 2) deficiency in the number of pancreatic beta
cells. The number of islet beta cells present at birth is mainly generated by the ... Cited by 118 - Related articles - BL Direct - All 6 versions
T Bock, B Pakkenberg, K Buschard - Diabetes, 2003 - Am Diabetes Assoc It is important for our understanding of the pancreatic islets to study whether new islets are able
to form in the intact pancreas. We developed a new method to determine the total number and
the mean volume of the pancreatic islets, and we used this method to study the expansion ... Cited by 57 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org T Bock, B Pakkenberg, K Buschard - Diabetes, 2005 - Am Diabetes Assoc Key parameters of the endocrine pancreas, such as islet number, islet mass, β-cell mass, and
α-cell mass, were studied in different strains of inbred mice to investigate the impact of genetic
background on the size and structure of the endocrine pancreas. Six mice from each of ... Cited by 23 - Related articles - All 6 versions
T Alanentalo, A Asayesh, H Morrison, CE Loren, D … - Nature methods, 2007 - ncbi.nlm.nih.gov A convenient technology to quantify three-dimensional (3D) morphological features would have
widespread applications in biomedical research. Based on combined improvements in sample
preparation, tomographic imaging and computational processing, we present a ... Cited by 18 - Related articles - BL Direct - All 3 versions
T Bock, B Pakkenberg, K Buschard - Apmis, 2003 - interscience.wiley.com Glucagon-like peptide 1 (GLP-1) and GLP-1 receptor agonists increase the beta-cell mass in
rodent models of type 2 diabetes and enhance the proliferation rate of beta cells in vitro, while
the long-term effect in vivo in non-diabetic animals is unknown. We studied the endocrine ... Cited by 15 - Related articles - BL Direct - All 4 versions
R Bottino, AN Balamurugan, C Smetanka, S … - …, 2007 - interscience.wiley.com Abstract: Introduction: Pig islets have been proposed as an alternative to human islets for clinical
use, but their use is limited by rejection. The availability of genetically modified pigs devoid of
α1,3-galactosyltransferase might provide islets more suitable for xenotransplantation. To ... Cited by 12 - Related articles - BL Direct - All 3 versions
K Josefsen, MD Nielsen, KH Jorgensen, T … - Journal of …, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 7 - Related articles - BL Direct - All 3 versions
T Bock - Bioessays, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] C Cannings - The American Journal of Human Genetics, 1998 - Elsevier Génin and Clerget-Darpoux recently discussed the derivation of the probabilities of identity states
for populations in which there was some degree of kinship, primarily to allow the extension of
the classical affected-sib-pair method to such populations. It is argued here that their ... Cited by 5 - Related articles - BL Direct - All 14 versions
