CC Strom, M Aplin, T Ploug, TE Christoffersen, J … - FEBS J, 2005 - interscience.wiley.com While cardiac hypertrophy elicited by pathological stimuli eventually leads to cardiac
dysfunction, exercise-induced hypertrophy does not. This suggests that a beneficial hypertrophic
phenotype exists. In search of an underlying molecular substrate we used microarray ... Cited by 28 - Related articles - All 4 versions
Y Gao, K Walder, T Sunderland, L Kantham, HC Feng, … - Diabetes, 2003 - Am Diabetes Assoc Increased hepatic glucose output and decreased glucose utilization are implicated in the development
of type 2 diabetes. We previously reported that the expression of a novel gene, Tanis, was upregulated
in the liver during fasting in the obese/diabetic animal model Psammomys obesus. Here, ... Cited by 24 - Related articles - BL Direct - All 6 versions
T Sparsø, G Andersen, T Nielsen, KS Burgdorf, AP … - Diabetologia, 2008 - Springer Page 1. ARTICLE The GCKR rs780094 polymorphism is associated with elevated fasting
serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of
type 2 diabetes T. Sparsø & G. Andersen & T. Nielsen & KS Burgdorf & ... Cited by 22 - Related articles - BL Direct - All 4 versions
M Orho-Melander, O Melander, C Guiducci, P Perez- … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We performed association studies in 12 independent
cohorts comprising >45,000 individuals representing several ancestral groups (whites from Northern
and Southern Europe, whites from the US, African Americans from the US, Hispanics of ... Cited by 21 - Related articles - All 11 versions
L Chan, M Fujimiya, H Kojima - Trends in Molecular Medicine, 2003 - Elsevier Gene therapy has been hyped as a possible 'cure' for diabetes mellitus in the near future ever
since insulin was first cloned and expressed in cultured cells in the late 1970s. In the past
decade, however, the bar for gene therapy for diabetes has been raised because of ... Cited by 19 - Related articles - All 3 versions
- ►endojournals.org JJ Collier, DK Scott - Molecular Endocrinology, 2004 - Endocrine Soc The liver is responsible for glucose synthesis in the fasting state, and glucose uptake,
storage, and utilization in the fed state. A phenotypic switch, normally initiated by insulin or
glucagon, controls the transition between the two states, which includes transcriptional ... Cited by 18 - Related articles - BL Direct - All 8 versions
R Yang, CB Newgard - … and glycemic diseases: from basics to novel …, 2004 - books.google.com GLUT2 Glucose Fig. 1. Regulatory steps in control of the balance between glucose disposal
and glu- cose production in liver. The figure shows some of the key regulatory steps controlling
hepatic glucose disposal and production, and emphasizes how these steps are ... Cited by 9 - Related articles - All 3 versions
K Tamada, XP Wang, FC Brunicardi - World journal of surgery, 2005 - Springer Abstract. During the last decade significant advances in gene therapy have made it possible
to treat various pancreatic disorders in both animal models and in humans. For example, insulin
gene delivery to non-b-cell tissues has been shown to reverse hyperglycemia in diabetic ... Cited by 10 - Related articles - All 3 versions
M Vaxillaire, C Cavalcanti-Proença, A Dechaume, J … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Hepatic glucokinase (GCK) is a key regulator of glucose storage and disposal
in the liver, where its activity is competitively modulated, with respect to glucose, by binding to
glucokinase regulatory protein (GCKR) in the presence of fructose 6-phosphate. Genome- ... Cited by 9 - Related articles - All 4 versions
G Dailey - Diabetes Obes Metab, 2008 - interscience.wiley.com The management of type 2 diabetes mellitus (T2DM) typically focuses on correcting dysglycaemia
to reduce risk for microvascular and macrovascular complications, possibly by reducing
glucose-mediated oxidative stress. However, other cardiometabolic risk factors, including ... Cited by 5 - Related articles - All 4 versions
