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Scholar Results 1 - 10 of about 54 citing Takano: Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol.... (0.09 sec) 

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes


M Fasshauer, J Klein, S Neumann, M … - Biochemical and Biophysical Research …, 2002 - Elsevier
Recently, it has been demonstrated that the fat-derived protein adiponectin is
an important insulin-sensitizing adipocytokine which is downregulated in insulin
resistance and obesity and replenishment of which in adiponectin-deficient ...
Cited by 399 - Related articles - BL Direct - All 5 versions

Tumor necrosis factor α is a negative regulator of resistin gene expression and secretion in …


M Fasshauer, J Klein, S Neumann, M … - Biochemical and biophysical research communications, 2001 - Elsevier
Resistin has recently been implicated as an adipocytokine leading to insulin
resistance and, therefore, potentially linking obesity and diabetes. To further
characterize the regulation of this fat-secreted protein by insulin ...
Cited by 146 - Related articles - BL Direct - All 5 versions

Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes

- endocrinology-journals.org
S Kralisch, J Klein, U Lossner, M Bluher, R … - Journal of Endocrinology, 2005 - Soc Endocrinology
Recently, visfatin was characterized as a novel adipo-cytokine that is
upregulated in obesity and exerts insulin-mimetic effects in various tissues. To
clarify expression and regulation of this adipocytokine, visfatin mRNA was ...
Cited by 127 - Related articles - All 2 versions

Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling


H Shi, I Tzameli, C Bjoerbaek, JS Flier - Journal of Biological Chemistry, 2004 - ASBMB
Many proinflammatory cytokines and hormones have been demonstrated to be
involved in insulin resistance. However, the molecular mechanisms whereby these
cytokines and hormones inhibit insulin signaling are not completely ...
Cited by 92 - Related articles - BL Direct - All 4 versions

Attenuation of leptin and insulin signaling by SOCS proteins

- cell.com
JK Howard, JS Flier - Trends in Endocrinology & Metabolism, 2006 - Elsevier
Leptin and insulin are key hormones involved in the regulation of energy balance
and glucose homeostasis. Development of resistance to the action of these
hormones, which can occur with age, obesity and inflammation, appears to ...
Cited by 69 - Related articles - All 12 versions

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes


M Fasshauer, J Klein, S Kralisch, M Klier, U … - FEBS letters, 2004 - Elsevier
The fat-derived protein adiponectin is an important insulin-sensitizing
adipocytokine which is downregulated in insulin resistance and obesity.
Recently, two receptors of this adipose-expressed protein called ...
Cited by 63 - Related articles - All 7 versions

Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling …

- endojournals.org
F Tremblay, AM Gagnon, A Veilleux, A Sorisky … - Endocrinology, 2005 - Endocrine Soc
The mammalian target of rapamycin (mTOR) pathway has recently emerged as a
chronic modulator of insulin-mediated glucose metabolism. In this study, we
evaluated the involvement of this pathway in the acute regulation of ...
Cited by 63 - Related articles - All 3 versions

Growth hormone-induced alterations in the insulin-signaling system

- ebmonline.org
FP Dominici, D Turyn - Experimental Biology and Medicine, 2002 - SEBM
Growth hormone (GH) counteracts insulin action on lipid and glucose metabolism.
However, the sequence of molecular events leading to these changes is poorly
understood. Insulin action is initiated by binding of the hormone to its ...
Cited by 62 - Related articles - BL Direct - All 4 versions

Human placental growth hormone increases expression of the p85 regulatory unit of …

- endojournals.org
LA Barbour, J Shao, L Qiao, W Leitner, M … - Endocrinology, 2004 - Endocrine Soc
The insulin resistance of normal pregnancy is necessary to divert fuels to the
fetus to meet fetal growth demands and is mediated by placental hormones. We
recently demonstrated that human placental GH (hPGH) can trigger severe ...
Cited by 59 - Related articles - BL Direct - All 4 versions

Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and …


M Fasshauer, J Klein, S Kralisch, M Klier, U … - Biochemical and Biophysical Research …, 2004 - Elsevier
During the last 10 years, various adipocytokines have been described which
influence insulin sensitivity profoundly and might, therefore, potentially link
obesity and insulin resistance. Recently, monocyte chemoattractant protein ...
Cited by 53 - Related articles - All 3 versions


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