- ►diabetesjournals.org A Ceriello - Diabetes care, 2003 - Am Diabetes Assoc Evidence implicates hyperglycemia-derived oxygen free radicals as mediators of
diabetic complications. However, intervention studies with classic antioxidants,
such as vitamin E, failed to demonstrate any beneficial effect. Recent ... Cited by 285 - Related articles - All 9 versions
D Ziegler, H Nowak, P Kempler, P Vargha, … - Diabetic Medicine, 2004 - ecopharm.bg Page 1. Treatment of symptomatic diabetic polyneuropathy with the antioxidant
a-lipoic acid: A meta-analysis D. Ziegler1, H. Nowak2, and PA Low3 ... Cited by 178 - Related articles - View as HTML - BL Direct - All 10 versions
- ►endojournals.org AM Vincent, JW Russell, P Low, EL Feldman - Endocrine reviews, 2004 - Endocrine Soc Oxidative stress results from a cell or tissue failing to detoxify the free
radicals that are produced during metabolic activity. Diabetes is characterized
by chronic hyperglycemia that produces dysregulation of cellular ... Cited by 139 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org D Ziegler, A Ametov, A Barinov, PJ Dyck, I … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—In this multicenter, randomized, double-blind,
placebo-controlled trial, 181 diabetic patients in Russia and Israel received
once-daily oral doses of 600 mg (n = 45) (ALA600), 1,200 mg (n = 47) ... Cited by 97 - Related articles - BL Direct - All 6 versions
IG Obrosova, F Li, OI Abatan, MA Forsell, K … - Diabetes, 2004 - Am Diabetes Assoc Oxidative and nitrosative stress play a key role in the pathogenesis of diabetic
neuropathy, but the mechanisms remain unidentified. Here we provide evidence
that poly(ADP-ribose) polymerase (PARP) activation, a downstream effector ... Cited by 87 - Related articles - BL Direct - All 10 versions
P Pacher, IG Obrosova, JG Mabley, C Szabó - Current medicinal chemistry, 2005 - pubmedcentral.nih.gov Macro- and microvascular disease are the most common causes of morbidity and
mortality in patients with diabetes mellitus. Diabetic cardiovascular
dysfunction represents a problem of great clinical importance underlying ... Cited by 80 - Related articles - All 9 versions
- ►nih.gov IG Obrosova, P Pacher, C Szabó, Z … - Diabetes, 2005 - Am Diabetes Assoc This study evaluated the effects of aldose reductase inhibition on
diabetes-induced oxidative-nitrosative stress and poly(ADP-ribose) polymerase
(PARP) activation. In animal experiments, control and ... Cited by 73 - Related articles - All 8 versions
MA Yorek - Free radical research, 2003 - informahealthcare.com This review will focus on the impact of hyperglycemia- induced oxidative stress
in the development of diabetes- induced vascular and neural dysfunction.
Oxidative stress occurs when the balance between the production of ... Cited by 74 - Related articles - BL Direct - All 8 versions
AM Vincent, JA Olzmann, M Brownlee, WI … - Diabetes, 2004 - Am Diabetes Assoc The central role of mitochondria in most pathways leading to programmed cell
death (PCD) has focused our investigations into the mechanisms of
glucose-induced neuronal degeneration. It has been postulated that ... Cited by 72 - Related articles - BL Direct - All 4 versions
