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Scholar Results 1 - 10 of about 36 citing Shike: Susceptibility and negative epistatic loci contributing to type 2 diabetes and related.... (0.13 sec) 

[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel, G … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN
WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE“RUSSE, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2005 update. Obesity. 2006;14: ...
Cited by 335 - Related articles - View as HTML - All 6 versions

The human obesity gene map: the 2002 update


YC Chagnon, T Rankinen, EE Snyder, SJ Weisnagel, L … - Obesity, 2003 - nature.com
This is the ninth update of the human obesity gene map, incorporating published results through
October 2002 and continuing the previous format. Evidence from single-gene mutation obesity
cases, Mendelian disorders exhibiting obesity as a clinical feature, quantitative trait loci ( ...
Cited by 226 - Related articles - BL Direct - All 6 versions

[PDF] Animal models of diabetes mellitus


DA Rees, JC Alcolado - Diabetic Medicine, 2005 - cms1.daegu.ac.kr
Animal experimentation has a long history in the field of dia- betes research. The aim of this article
is to review the commonly used animal models and discuss the recent technological advances
that are being employed in the discipline. The review is based on an extensive literature ...
Cited by 97 - Related articles - View as HTML - All 7 versions

Genetics of variation in HDL cholesterol in humans and mice

- ahajournals.org [PDF] 
X Wang, B Paigen - Circulation research, 2005 - Am Heart Assoc
Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... This Review is part of a thematic series on New Pathways in HDL ...
Cited by 56 - Related articles - All 8 versions

Haplotype analysis in multiple crosses to identify a QTL gene

- 171.66.122.45
X Wang, R Korstanje, D Higgins, B Paigen - Genome research, 2004 - 171.66.122.45
Identifying quantitative trait locus (QTL) genes is a challenging task. Herein, we report using
a two-step process to identify Apoa2 as the gene underlying Hdlq5, a QTL for plasma high-density
lipoprotein cholesterol (HDL) levels on mouse chromosome 1. First, we performed a ...
Cited by 50 - Related articles - BL Direct - All 10 versions

Candesartan reduced advanced glycation end-products accumulation and …

- oxfordjournals.org
Q Fan, J Liao, M Kobayashi, M Yamashita, L Gu, … - Nephrology Dialysis …, 2004 - ERA-EDTA
Methods. KK/Ta mice were divided into three treatment groups: an early treatment group receiving
4 mg/kg/day candesartan from 6 to 28 weeks of age, a late treatment group receiving the same
candesartan dose from 12 to 28 weeks of age and a group receiving the vehicle for ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Identification of Epistatic Interaction Involved in Obesity Using the KK/Ta Mouse as …

- diabetesjournals.org
T Gohda, Y Makita, T Shike, M Tanimoto, K Funabiki, S … - Diabetes, 2003 - Am Diabetes Assoc
The KK/Ta strain serves as a suitable polygenic mouse model for the common form of type 2
diabetes associated with obesity in humans. Recently, we reported the susceptibility loci contributing
to type 2 diabetes and related phenotypes in KK/Ta mice. In this study, we focused on ...
Cited by 39 - Related articles - BL Direct - All 4 versions

Genome-wide search for new genes controlling plasma lipid concentrations in …

- nursing2008.com [PDF] 
X Wang, B Paigen - Current opinion in lipidology, 2005 - journals.lww.com
Purpose of review Quantitative trait locus analysis has been used in both humans and mice for
the purpose of finding new genes regulating plasma lipid levels. We review these methods and
discuss new approaches that can help find quantitative trait locus genes. Recent findings ...
Cited by 33 - Related articles - All 6 versions

Effect of pioglitazone on the early stage of type 2 diabetic nephropathy in KK/Ta …


M Tanimoto, Q Fan, T Gohda, T Shike, Y Makita, Y … - Metabolism, 2004 - Elsevier
Pioglitazone (PIO) has preventive effects on impaired glucose tolerance (IGT) and urinary albumin
excretion in diabetes. These effects in the early stage of diabetic nephropathy have not been
fully described. Endothelial constitutive nitric oxide synthase (ecNOS) might be one of the ...
Cited by 29 - Related articles - All 10 versions

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human population. Like
humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse strains
differ in the response of their critical physiological functions, such as insulin sensitivity, ...
Cited by 29 - Related articles - BL Direct - All 4 versions


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