C Marzolini, E Paus, T Buclin, RB Kim - Clinical Pharmacology & Therapeutics, 2004 - nature.com Drug transporters are increasingly recognized to be important to drug
disposition and response. P-glycoprotein, the encoded product of the human MDR1
(ABCB1) gene, is of particular clinical relevance in that this transporter ... Cited by 454 - Related articles - All 6 versions
MJ Cork, DA Robinson, Y Vasilopoulos, A … - The Journal of Allergy and Clinical Immunology, 2006 - Elsevier Atopic dermatitis (AD) is a multifactorial, chronic inflammatory skin disorder
in which genetic mutations and cutaneous hyperreactivity to environmental
stimuli play a causative role. Genetic mutations alone might not be enough ... Cited by 127 - Related articles - All 60 versions
- ►nih.gov R Di Paola, L Frittitta, G Miscio, M Bozzali, R … - The American Journal of Human Genetics, 2002 - Elsevier Protein tyrosine phosphatase 1B (PTP1B) inhibits insulin signaling and, when
overexpressed, plays a role in insulin resistance (Ahmad et al. 1997). We
identified, in the 3′ untranslated region of the PTP1B gene, a 1484insG ... Cited by 104 - Related articles - BL Direct - All 4 versions
JW Goding, B Grobben, H Slegers - BBA-Molecular Basis of Disease, 2003 - Elsevier The ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP) multigene family
contains five members. NPP1-3 are type II transmembrane metalloenzymes
characterized by a similar modular structure composed of a short ... Cited by 100 - Related articles - All 4 versions
- Free from Publisher ZT Bloomgarden - Diabetes Care, 2003 - cat.inist.fr American Association of Clinical Endocrinologists(AACE) Consensus Conference on
the Insulin Resistance Syndrome: 25-26 August 2002, Washington, DC. ... Cited by 68 - Related articles - BL Direct - All 6 versions
Y Vasilopoulos, MJ Cork, R Murphy, HC … - Journal of Investigative Dermatology, 2003 - nature.com Atopic dermatitis is a disease with an impaired skin barrier that affects
15%–20% of children. In the normal epidermis, the stratum corneum chymotryptic
enzyme (SCCE) thought to play a central role in desquamation by cleaving ... Cited by 67 - Related articles - BL Direct - All 4 versions
- ►kuleuven.be [PDF] C Stefan, S Jansen, M Bollen - Trends in biochemical sciences, 2005 - Elsevier Nucleotide pyrophosphatase/phosphodiesterase (NPP)-type ectophosphodiesterases
are found at the cell surface as type-I or type-II transmembrane proteins, but
are also found extracellularly as secreted or shedded enzymes. They ... Cited by 57 - Related articles - All 8 versions
E Filippi, F Sentinelli, V Trischitta, S Romeo, … - European Journal of Human Genetics, 2003 - nature.com Adiponectin is an adipocyte-secreted protein that modulates insulin sensitivity
and whose low circulating concentration is associated with insulin resistance.
In the present study, we analysed the association between two ... Cited by 54 - Related articles - BL Direct - All 4 versions
LH Canani, DPK Ng, A Smiles, JJ Rogus, JH … - Diabetes, 2002 - Am Diabetes Assoc A polymorphism in the ecto-nucleotide pyrophosphatase/phosphodiesterase 1 gene
(ENPP1) (previously known as PC-1), resulting in an amino acid change from
lysine to glutamine at codon 121 (K121Q), is associated with insulin ... Cited by 42 - Related articles - BL Direct - All 4 versions
