- ►physiology.org SW Ryter, J Alam, AMK Choi - Physiological reviews, 2006 - Am Physiological Soc The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1,
HO-2), catalyze the rate-limiting step in the metabolic conversion of heme to
the bile pigments (ie, biliverdin and bilirubin) and thus constitute a ... Cited by 343 - Related articles - BL Direct - All 6 versions
- ►aspetjournals.org FA Wagener, HD Volk, D Willis, NG Abraham, … - Pharmacological reviews, 2003 - ASPET Heme oxygenase (HO 2 ), the heme-degrading enzyme, however, obtained only scarce
attention after its discovery in 1968 (Tenhunen et al., 1968 Go ), but during
the last 10 years, this enzyme has rapidly gained interest from a fast ... Cited by 195 - Related articles - BL Direct - All 8 versions
M Katori, RW Busuttil, JW Kupiec-Weglinski - Transplantation, 2002 - journals.lww.com 2 Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation,
University of California at Los Angeles, Los Angeles, CA. ... 3 Address
correspondence to: Jerzy W. Kupiec-Weglinski, MD Ph.D., Dumont-UCLA ... Cited by 165 - Related articles - BL Direct - All 3 versions
NG Abraham, A Kappas - Free Radical Biology and Medicine, 2005 - Elsevier Heme oxygenase (HO) has been shown to be important for attenuating the overall
production of reactive oxygen species (ROS) through its ability to degrade heme
and to produce carbon monoxide (CO), biliverdin/bilirubin, and the release ... Cited by 145 - Related articles - All 3 versions
- ►amjpathol.org T Fujikawa, SH Oh, L Pi, HM Hatch, T Shupe, … - American Journal of Pathology, 2005 - ASIP Embryonic stem (ES) cells have been proposed to be a powerful tool in the study
of pancreatic disease, as well as a potential source for cell replacement
therapy in the treatment of diabetes. However, data demonstrating the ... Cited by 138 - Related articles - All 8 versions
M Exner, E Minar, O Wagner, M Schillinger - Free Radical Biology and Medicine, 2004 - Elsevier Heme oxygenase (HO) seems to be a novel protective factor with potent
anti-inflammatory, anti-oxidant, and anti-proliferative effects. HO-1, the
inducible isoform, is expressed in various tissues and is upregulated by ... Cited by 128 - Related articles - All 3 versions
JF Markmann, S Deng, X Huang, NM Desai, EH … - Annals of surgery, 2003 - pubmedcentral.nih.gov The recent report by the Edmonton group documenting restoration of insulin
independence by islet transplantation in seven consecutive patients with type 1
diabetes differed from previous worldwide experience of only sporadic ... Cited by 121 - Related articles - BL Direct - All 7 versions
- ►amjpathol.org MH Kapturczak, C Wasserfall, T Brusko, M … - American Journal of Pathology, 2004 - ASIP Induction of heme oxygenase-1 (HO-1) is protective in tissue injury in models of
allograft rejection and vascular inflammation through either prevention of
oxidative damage or via immunomodulatory effects. To examine the specific ... Cited by 119 - Related articles - BL Direct - All 4 versions
W Durante - Journal of cellular physiology, 2003 - interscience.wiley.com Heme oxygenase-1 (HO-1) catalyzes the degradation of heme to carbon monoxide
(CO), iron, and biliverdin. Biliverdin is subsequently metabolized to bilirubin
by the enzyme biliverdin reductase. Although interest in HO-1 originally ... Cited by 107 - Related articles - BL Direct - All 4 versions
