- ►tamu.edu [PDF] C King, A Ilic, K Koelsch, N Sarvetnick - Cell, 2004 - Elsevier During illness and stress, the immune system can suffer a considerable loss of T
cells (lymphopenia). The remaining T cells undergo vigorous compensatory
expansion, known as homeostatic proliferation, to reconstitute the immune ... Cited by 296 - Related articles - All 14 versions
- ►pnas.org SM Lieberman, AM Evans, B Han, T Takaki, Y … - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences Type 1 diabetes is an autoimmune disease in which autoreactive T cells attack
and destroy the insulin-producing pancreatic β cells. CD8 + T cells are
essential for this β cell destruction, yet their specific antigenic ... Cited by 175 - Related articles - BL Direct - All 11 versions
D Serreze, EH Letter - Molecular Pathology of Type 1 Diabetes mellitus - books.google.com The'Idd'Genes: What Are They and How Many Are Required for Diabetogenesis? In
order to describe murine chromosomal regions carrying genes capable of
modulating T1D susceptibility when NOD/Lt mice were outcrossed to the ... Cited by 70 - Related articles - BL Direct - All 5 versions
KV Tarbell, M Lee, E Ranheim, CC Chao, M … - Journal of Experimental Medicine, 2002 - jem.rupress.org Glutamic acid decarboxylase (GAD)65 is an early and important antigen in both
human diabetes mellitus and the nonobese diabetic (NOD) mouse. However, the
exact role of GAD65-specific T cells in diabetes pathogenesis is unclear. T ... Cited by 62 - Related articles - BL Direct - All 7 versions
PA Silveira, E Johnson, HD Chapman, T Bui, … - European journal of immunology, 2002 - interscience.wiley.com B lymphocytes partially contribute to autoimmune type 1 diabetes (T1D) as a
subset of APC with a preferential ability to trigger pathogenic CD4 T cells. We
hypothesized that this resulted fromthe unique ability of B lymphocytes to ... Cited by 56 - Related articles - BL Direct - All 4 versions
R Mukherjee, P Chaturvedi, HY Qin, B Singh - Journal of Autoimmunity, 2003 - Elsevier NOD mice have a relative deficiency of CD4 + CD25 + regulatory T cells that
could result in an inability to maintain peripheral tolerance. The aim of this
study was to induce the generation of CD4 + CD25 + regulatory T cells in ... Cited by 50 - Related articles - All 4 versions
- ►highwire.org AM Marleau, N Sarvetnick - Journal of leukocyte biology, 2005 - jleuk.highwire.org The size of the peripheral T cell pool is remarkably stable throughout life,
reflecting precise regulation of cellular survival, proliferation, and
apoptosis. Homeostatic proliferation refers to the process by which T cells ... Cited by 44 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org CM Choisy-Rossi, TM Holl, MA Pierce, HD … - The Journal of Immunology, 2004 - Am Assoc Immnol For unknown reasons, the common MHC class I variants encoded by the H2 g7
haplotype (K d , D b ) aberrantly elicit autoreactive CD8 T cell responses
essential to type 1 diabetes development when expressed in NOD mice, but ... Cited by 27 - Related articles - BL Direct - All 4 versions
- ►pnas.org P Serra, A Amrani, B Han, J Yamanouchi, SJ … - Proceedings of the National Academy of Sciences, 2002 - National Acad Sciences Rearrangement of T cell receptor (TCR) genes is driven by transient expression
of V(D)J recombination-activating genes (RAGs) during lymphocyte development.
Immunological dogma holds that T cells irreversibly terminate RAG ... Cited by 24 - Related articles - BL Direct - All 8 versions
TP DiLorenzo, SM Lieberman, T Takaki, S … - Clinical Immunology, 2002 - Elsevier In the NOD mouse model of type 1 diabetes, major histocompatibilitycomplex (MHC)
class I-restricted CD8 + T cells are essential for disease development. However,
the extent of diversity of their antigenic specificities during early ... Cited by 24 - Related articles - BL Direct - All 4 versions
