A Suzuki, H Nakauchi, H Taniguchi - Diabetes, 2004 - Am Diabetes Assoc During pancreatic development, neogenesis, and regeneration, stem cells might act as a central
player to generate endocrine, acinar, and duct cells. Although these cells are well known as
pancreatic stem cells (PSCs), indisputable proof of their existence has not been reported. ... Cited by 138 - Related articles - BL Direct - All 4 versions
- ►physiology.org JF List, JF Habener - American Journal of Physiology- …, 2004 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is an intestine-derived insulinotropic hormone that stimulates
glucose-dependent insulin production and secretion from pancreatic -cells. Other recognized
actions of GLP-1 are to suppress glucagon secretion and hepatic glucose output, delay ... Cited by 43 - Related articles - BL Direct - All 3 versions
M Ohsugi, C Cras-Meneur, Y Zhou, E Bernal- … - Journal of Biological …, 2005 - ASBMB Running Title: Multiple roles of insulin signaling in islet cells ... Reduced Expression of the Insulin
Receptor in Mouse Insulinoma (MIN6) Cells Reveals Multiple Roles of Insulin Signaling in Gene
Expression, Proliferation, Insulin Content and Secretion. ... Mitsuru Ohsugi, Corentin ... Cited by 39 - Related articles - All 5 versions
NK Yashpal, J Li, R Wang - Developmental Dynamics, 2004 - interscience.wiley.com It has been well documented that there are abundant endocrine progenitor cells in the neonatal
pancreas. However, little is known of their relative proportions or even their phenotypes. The
aim of this study was to examine the normal distribution and characteristics of putative ... Cited by 30 - Related articles - All 3 versions
K Peters, R Panienka, J Li, G Klöppel, R Wang - Virchows Archiv, 2005 - Springer Abstract Ligation of the pancreatic duct has been shown to induce islet cell neogenesis from
duct cells in the adult rat pancreas. The transcription factors that regulate islet cell neogenesis
and the phenotype of putative precursor cells involved in neogenesis are unknown. We, ... Cited by 30 - Related articles - All 3 versions
- ►nih.gov [PDF] VM Lee, M Stoffel - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Diabetes, a leading cause of morbidity and mortality in industrialized countries, is caused by
an absolute insulin deficiency due to the destruction of insulin secreting pancreatic β cells (type
1 diabetes) or by a relative insulin deficiency due to decreased insulin sensitivity, usually ... Cited by 27 - Related articles - BL Direct - All 7 versions
NK Yashpal, J Li, MB Wheeler, R Wang - Endocrinology, 2005 - Endocrine Soc The integrin receptors link to extracellular matrix proteins and exert a dynamic role in development
by providing the physical basis for cell adhesion and controlling cell growth. In the present
study, we examined changes in the expression of ß1 integrins and its associated ... Cited by 26 - Related articles - All 5 versions
- ►endojournals.org EA Joanette, B Reusens, E Arany, S Thyssen, RC … - Endocrinology, 2004 - Endocrine Soc Feeding a low-protein (LP) diet to pregnant and lactating rats impairs pancreatic islet mass and
insulin release in the offspring, leading to glucose intolerance as adults. We hypothesized that
an LP diet changes the number of pancreatic endocrine precursor cells or cells ... Cited by 24 - Related articles - BL Direct - All 8 versions
- ►endocrinology-journals.org [PDF] R Wang, J Li, N Yashpal - Journal of Endocrinology, 2004 - Soc Endocrinology The limitation of available islets for transplantation is a major obstacle for the treatment of diabetes
through islet therapy. However, islet monolayers expanded ex vivo may provide a source of progenitor
cells and a model to help understand islet development from precursor cell types. The ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org S Srivastava, HJ Goren - Diabetes, 2003 - Am Diabetes Assoc Four hypotheses have been posited on the role of insulin in glucose-stimulated insulin
secretion; available evidence has supported insulin as being 1) essential, 2) a positive
modulator, 3) a negative modulator, or 4) not necessary. Because circulating insulin ... Cited by 19 - Related articles - BL Direct - All 4 versions
