- ►imbice.org.ar [PDF] AD Bolzán, MS Bianchi - Mutation Research-Reviews in Mutation Research, 2002 - Elsevier Streptozotocin (Streptozocin, STZ, CAS No. 18883-66-4) is a monofunctional
nitrosourea derivative isolated from Streptomyces achromogenes. It has broad
spectrum antibiotic activity and antineoplastic properties and is often ... Cited by 87 - Related articles - All 8 versions
- ►nih.gov [PDF] H Raza, MA Robin, JK Fang, NG Avadhani - Biochemical Journal, 2002 - pubmedcentral.nih.gov The mitochondrial respiratory chain, which consumes approx. 85–90% of the
oxygen utilized by cells, is a major source of reactive oxygen species (ROS).
Mitochondrial genetic and bio- synthetic systems are highly susceptible to ... Cited by 74 - Related articles - BL Direct - All 9 versions
X Li, H Chen, PN Epstein - Journal of Biological Chemistry, 2004 - ASBMB Islet transplantation is a promising therapy for Type 1 diabetes, but many
attempts have failed due to early graft hypoxia or immune rejection, which
generate reactive oxygen species (ROS). In the current study, we determined ... Cited by 66 - Related articles - BL Direct - All 5 versions
M Penkowa, J Hidalgo - Journal of neuroscience research, 2003 - interscience.wiley.com Experimental autoimmune encephalomyelitis (EAE) is an animal model for the human
demyelinating disease multiple sclerosis (MS). EAE and MS are characterized by
significant inflammation, demyelination, neuroglial damage, and cell death. ... Cited by 43 - Related articles - BL Direct - All 3 versions
LB Køhler, V Berezin, E Bock, M Penkowa - Brain research, 2003 - Elsevier Metallothionein I and II (MT-I+II) are antioxidant and tissue protective
factors. We have previously shown that MT-I+II prevent oxidative stress and
apoptotic cell death and are of therapeutic value in brain inflammation. ... Cited by 39 - Related articles - All 4 versions
- ►diabetesjournals.org H Chen, X Li, PN Epstein - Diabetes, 2005 - Am Diabetes Assoc Reactive oxygen species (ROS) and nitric oxide (NO) are proposed mediators of
cytokine-induced β-cell destruction in type 1 diabetes. We produced transgenic
mice with increased β-cell expression of manganese superoxide dismutase ... Cited by 34 - Related articles - All 6 versions
CG Taylor - Biometals, 2005 - Springer Molecular and cellular studies have demonstrated several roles for zinc (Zn) in
insulin production and the consequent actions of insulin on metabolism. Clinical
and epidemiological studies suggest that reduced Zn status is associated ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►ebmonline.org P Schott-Ohly, A Lgssiar, HJ Partke, M … - Experimental Biology and Medicine, 2004 - SEBM Recently, we reported that zinc sulfate-enriched (25 mM) drinking water (Zn 2+ )
protected male C57BL/6 mice from diabetes induced by multiple low doses of
streptozotocin (MLD-STZ) and that MLD-STZ activates the transcription ... Cited by 26 - Related articles - BL Direct - All 3 versions
ML Merchant, JB Klein - Current Diabetes Reports, 2005 - Springer Introduction Proteomics is rapidly progressing from a set of basic research
tools to a research paradigm for basic and applied sciences. The proteomic
approach requires the application of protein separation, mass spectrometry, ... Cited by 25 - Related articles - BL Direct - All 11 versions
- ►ebmonline.org MG Cherian, YJ Kang - Experimental Biology and Medicine, 2006 - SEBM Hepatocytes in adults are in a nonproliferative state but they have high
capacity to regenerate within few hours after an injury. After partial
hepatectomy or chemical injury, hepatocytes undergo a synchronized ... Cited by 25 - Related articles - BL Direct - All 3 versions
