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Scholar Results 1 - 10 of about 29 citing Williams: Interactions of impaired glucose transport and phosphorylation in skeletal muscle.... (0.17 sec) 

Pathogenesis of type 2 diabetes mellitus

- fafp.org [PDF] 
RA DeFronzo - Medical Clinics of North America, 2004 - Elsevier
A discussion of the pathogenesis of type 2 diabetes mellitus must start with a
review of mechanisms involved in the maintenance of normal glucose homeostasis
in the basal or postabsorptive state (10–12 h overnight fast) and ...
Cited by 692 - Related articles - BL Direct - All 5 versions

Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose …

- diabetesjournals.org
GW Cline, K Johnson, W Regittnig, P Perret, … - Diabetes, 2002 - Am Diabetes Assoc
Defects in liver and muscle glycogen synthesis are major factors contributing to
postprandrial hyperglycemia in patients with type 2 diabetes. Therefore,
activation of glycogen synthase through inhibition of glycogen synthase ...
Cited by 101 - Related articles - BL Direct - All 4 versions

Impaired glucose phosphorylation and transport in skeletal muscle cause insulin resistance in …

- nih.gov
GMN Behrens, AR Boerner, K Weber, J van … - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig
Insulin resistance is a frequently observed side effect of highly active
antiretroviral therapy (HAART). Currently, very little is known about the
mechanisms or specific tissues involved. We aimed to identify possible ...
Cited by 67 - Related articles - BL Direct - All 7 versions

Metabolic and molecular basis of insulin resistance


M Bajaj, RA DeFronzo - Journal of Nuclear Cardiology, 2003 - Elsevier
After the ingestion of a glucose-containing meal, the delicate balance between
endogenous glucose production and tissue glucose uptake is disrupted. The rise
in plasma glucose concentration stimulates the release of insulin from the ...
Cited by 31 - Related articles - All 4 versions

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in …

- nih.gov
YB Kim, OD Peroni, WG Aschenbach, Y … - Science's STKE, 2005 - stke.sciencemag.org
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Cited by 23 - Related articles - BL Direct - All 9 versions

Weight loss-induced plasticity of glucose transport and phosphorylation in the insulin …

- diabetesjournals.org
KV Williams, A Bertoldo, P Kinahan, C Cobelli … - Diabetes, 2003 - Am Diabetes Assoc
We tested the hypothesis that weight loss alleviates insulin resistance in
skeletal muscle within the proximal steps of glucose metabolism, namely
substrate delivery, glucose transport, and glucose phosphorylation. In ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Interaction of physiological mechanisms in control of muscle glucose uptake


DH Wasserman, JE Ayala - Clinical and Experimental Pharmacology and …, 2005 - interscience.wiley.com
1. Control of glucose uptake is distributed between three steps. These are the
rate that glucose is delivered to cells, the rate of transport into cells, and
the rate that glucose is phosphorylated within these same cells. The ...
Cited by 21 - Related articles - All 10 versions

Glucose transport and phosphorylation in skeletal muscle in obesity: insight from a muscle- …

- endojournals.org
KV Williams, A Bertoldo, B Mattioni, JC Price, … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
A controversial area in understanding the contribution of obesity to skeletal
muscle insulin resistance is the distribution of control of glucose metabolism
across proximal steps of glucose delivery, trans-membrane transport, and ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, …


PT Fueger, J Shearer, DP Bracy, KA Posey, … - The Journal of Physiology, 2005 - Physiological Soc
The aim of this study was to test whether in fact glucose transport is
rate-limiting in control of muscle glucose uptake (MGU) under physiological
hyperinsulinaemic conditions in the conscious, unrestrained mouse. C57Bl/6J ...
Cited by 19 - Related articles - BL Direct - All 9 versions

Glucose phosphorylation as a barrier to muscle glucose uptake


PT Fueger - Clinical and Experimental Pharmacology and …, 2005 - interscience.wiley.com
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Cited by 13 - Related articles - All 5 versions


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