- ►nih.gov KE Wellen, GS Hotamisligil - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Over the last decade, an abundance of evidence has emerged demonstrating a close
link between metabolism and immunity. It is now clear that obesity is associated
with a state of chronic low-level inflammation. In this article, we discuss ... Cited by 774 - Related articles - All 15 versions
AR Folgueras, AM Pendás, LM Sánchez, C … - International Journal of Developmental Biology, 2004 - ijdb.ehu.es ABSTRACT Over the last years, the relevance of the matrix metalloproteinase
(MMP) family in cancer research has grown considerably. These enzymes were
initially associated with the invasive properties of tumour cells, owing to ... Cited by 189 - Related articles - View as HTML - BL Direct - All 7 versions
KN Frayn, F Karpe, BA Fielding, IA … - International Journal of Obesity, 2003 - nature.com Adipose tissue is now recognised as a highly active metabolic and endocrine
organ. Great strides have been made in uncovering the multiple functions of the
adipocyte in cellular and molecular detail, but it is essential to remember ... Cited by 129 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org D Fukumura, A Ushiyama, DG Duda, L Xu, J Tam … - Circulation research, 2003 - Am Heart Assoc With an increasing incidence of obesity worldwide, rational strategies are
needed to control adipogenesis. Growth of any tissue requires the formation of a
functional and mature vasculature. To gain mechanistic insight into the ... Cited by 132 - Related articles - All 5 versions
- ►animal-science.org GJ Hausman, RL Richardson - Journal of animal science, 2004 - animal-science.org A review of adipose tissue angiogenesis includes the morphological and
cytochemical development of adipose tissue vasculature and the concept of
primitive fat organs. Spatial and temporal relationships between fetal ... Cited by 124 - Related articles - BL Direct - All 12 versions
- ►jbc.org C Chavey, B Mari, MN Monthouel, S Bonnafous … - Journal of Biological Chemistry, 2003 - ASBMB Matrix metalloproteinases (MMPs) are essential for proper extracellular matrix
remodeling, a process that takes place during obesity-mediated adipose tissue
formation. Here, we examine expression profiles and the potential role of ... Cited by 101 - Related articles - BL Direct - All 4 versions
- ►up.pt [PDF] M Lafontan, 2004 - Annual Reviews ▪ Abstract For a long time neural and endocrine messages were studied for
their impact on adipocyte metabolism and control of storage/release of fatty
acids. In fact, bidirectional communication exists between adipocytes and ... Cited by 80 - Related articles - BL Direct - All 7 versions
E Maquoi, C Munaut, A Colige, D Collen, HR … - Diabetes, 2002 - Am Diabetes Assoc The potential role of the matrix metalloproteinase (MMP) system in the
pathophysiology of the adipose tissue was investigated in a mouse model of
nutritionally induced obesity. mRNA levels of 16 MMPs and 4 tissue ... Cited by 73 - Related articles - BL Direct - All 6 versions
TH Chun, KB Hotary, F Sabeh, AR Saltiel, ED … - Cell, 2006 - Elsevier White adipose tissue (WAT) serves as the primary energy depot in the body by
storing fat. During development, fat cell precursors (ie, preadipocytes) undergo
a hypertrophic response as they mature into lipid-laden adipocytes. ... Cited by 63 - Related articles - All 12 versions
- ►nih.gov Y Cao - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Approximately 65% of adults in the United States and more than half of the
population in the rest of developed countries are overweight or obese (1). The
prevalence in children in all developed countries is about 15% and this ... Cited by 56 - Related articles - BL Direct - All 6 versions
