- ►nih.gov SP Weisberg, D McCann, M Desai, M … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Obesity alters adipose tissue metabolic and endocrine function and leads to an
increased release of fatty acids, hormones, and proinflammatory molecules that
contribute to obesity associated complications. To further characterize the ... Cited by 1731 - Related articles - BL Direct - All 16 versions
N Maeda, I Shimomura, K Kishida, H … - Nature medicine, 2002 - nature.com Here we investigated the biological functions of adiponectin/ACRP30, a
fat-derived hormone, by disrupting the gene that encodes it in mice.
Adiponectin/ACRP30-knockout (KO) mice showed delayed clearance of free ... Cited by 1088 - Related articles - BL Direct - All 6 versions
H Yki-Jarvinen - New England Journal of Medicine, 2004 - content.nejm.org Insulin resistance both precedes and predicts type 2 diabetes mellitus. 1
Although exercise and weight loss ameliorate insulin resistance and may in some
cases prevent or delay onset of the disease, 2 therapy that combats insulin ... Cited by 834 - Related articles - BL Direct - All 6 versions
- ►hopkinsmedicine.org [PDF] SE Kahn, SM Haffner, MA Heise, WH Herman, … - New England Journal of Medicine, 2006 - content.nejm.org From the Veterans Affairs Puget Sound Health Care System and University of
Washington, Seattle (SEK); University of Texas Health Science Center at San An
tonio, San Antonio (SMH); GlaxoSmith Kline, King of Prussia, PA (MAH, BGK, ... Cited by 767 - Related articles - BL Direct - All 30 versions
RS Lindsay, T Funahashi, RL Hanson, Y … - The Lancet, 2002 - Elsevier Adiponectin is a collagen-like circulating protein secreted by adipocytes that
is proposed to mediate obesity-related resistance to insulin. In a case-control
series, we assessed the role of adiponectin in later development of type 2 ... Cited by 704 - Related articles - All 5 versions
- ►ahajournals.org M Kumada, S Kihara, S Sumitsuji, T Kawamoto … - Arteriosclerosis, thrombosis, and vascular biology, 2003 - Am Heart Assoc Methods and Results— The consecutive 225 male patients were enrolled from
inpatients who underwent coronary angiography. Voluntary blood donors (n=225)
matched for age served as controls. Plasma adiponectin levels in the CAD ... Cited by 665 - Related articles - BL Direct - All 5 versions
- ►endojournals.org T Kadowaki, T Yamauchi - Endocrine Reviews, 2005 - Endocrine Soc Recently, we have cloned adiponectin receptors in the skeletal muscle (AdipoR1)
and liver (AdipoR2), which appear to comprise a novel cell-surface receptor
family. We showed that AdipoR1 and AdipoR2 serve as receptors for globular ... Cited by 619 - Related articles - All 8 versions
AH Berg, TP Combs, PE Scherer… - Trends in Endocrinology and Metabolism, 2002 - cell.com Adipose tissue has long been regarded as a mostly resting tissue that is
dedicated solely to energy storage and release. However, in recent years, this
view has changed dramatically following new insights into the metabolic and ... Cited by 571 - Related articles - Cached - BL Direct - All 6 versions
T Yamauchi, J Kamon, H Waki, Y Imai, N … - Journal of Biological Chemistry, 2003 - ASBMB The adipocyte-derived hormone adiponectin has been shown to play important roles
in the regulation of energy homeostasis and insulin sensitivity. In this study,
we analyzed globular domain adiponectin (gAd) transgenic (Tg) mice crossed ... Cited by 568 - Related articles - BL Direct - All 10 versions
M Cnop, PJ Havel, KM Utzschneider, DB Carr, … - Diabetologia, 2003 - Springer Aims/hypothesis. Increased intra-abdominal fat is as- sociated with insulin
resistance and an atherogenic li- poprotein profile. Circulating concentrations
of adip- onectin, an adipocyte-derived protein, are decreased with insulin ... Cited by 523 - Related articles - BL Direct - All 5 versions
