- ►uoguelph.ca [PDF] MJ Sheetz, GL King - Jama, 2002 - Am Med Assoc Diabetic complications are the major cause of morbidity and mortality in persons
with diabetes. Chronic hyperglycemia is a major initiator of diabetic
microvascular complications (eg, retinopathy, neuropathy, nephropathy). ... Cited by 375 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org HB Lee, MR Yu, Y Yang, Z Jiang, H Ha - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Diabetic nephropathy is characterized by excessive deposition of extracellular
matrix (ECM) in the kidney, leading to glomerular mesangial expansion and
tubulointerstitial fibrosis. Clinical studies (1,2) have demonstrated that ... Cited by 174 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org RM Mason, NA Wahab - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Diabetes mellitus has recently assumed epidemic proportions, partly due to the 2
to 5% increase in the incidence of type 1 diabetes in children, but especially
due to the global increase in type 2 diabetes (1). Currently as many as 4% ... Cited by 159 - Related articles - BL Direct - All 9 versions
AW Stitt - Experimental and molecular pathology, 2003 - Elsevier Retinopathy is one of the commonest microvascular complications of diabetes and
is still the prevailing cause of registerable blindness in the working
population of developed countries. The clinicopathology of microvascular ... Cited by 84 - Related articles - All 5 versions
- ►physiology.org [PDF] BPS Kang, S Frencher, V Reddy, A Kessler, A … - American Journal of Physiology- Renal Physiology, 2003 - Am Physiological Soc 47 articles, 22 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/284/3/F455#BIBL ... 22 other
HighWire hosted articles, the first 5 are: This article has been cited by Cited by 78 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org FR DeRubertis, PA Craven, MF Melhem, EM … - Diabetes, 2004 - Am Diabetes Assoc The effects of overexpression of Cu 2+ /Zn 2+ superoxide dismutase-1 (SOD-1) on
indexes of renal injury were compared in 5-month-old nontransgenic (NTg) db/db
mice and db/db mice hemizygous for the human SOD-1 transgene (SOD-Tg). Both ... Cited by 59 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org MF Melhem, PA Craven, J Liachenko, FR … - Journal of the American Society of Nephrology, 2002 - Am Soc Nephrol ABSTRACT. Previous studies demonstrated that 2 mo of dietary supplementation
with -lipoic acid (LA) prevented early glomerular injury in non-insulin-treated
streptozotocin diabetic rats (D). The present study examined the effects of ... Cited by 62 - Related articles - BL Direct - All 5 versions
- ►physiology.org AR Diani, G Sawada, B Wyse, FT Murray, M … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Thiazolidinediones may slow the progression of type 2 diabetes by preserving
pancreatic -cells. The effects of pioglitazone (PIO) on structure and function
of -cells in KKA(y), C57BL/6J ob/ob, and C57BL/KsJ db/db mice (genetic ... Cited by 57 - Related articles - BL Direct - All 4 versions
AD Hodgkinson, T Bartlett, PJ Oates, BA … - Diabetes, 2003 - Am Diabetes Assoc Increased flux of glucose through the polyol pathway may cause generation of
excess reactive oxygen species (ROS), leading to tissue damage. Abnormalities in
expression of enzymes that protect against oxidant damage may accentuate ... Cited by 55 - Related articles - BL Direct - All 4 versions
H Ha, HB Lee - Current Diabetes Reports, 2001 - Springer Introduction Clinical studies demonstrated that high blood glucose is the main
determinant of initiation and progression of diabetic vascular complications.
Diabetic nephropathy is the leading cause of end-stage renal disease ... Cited by 55 - Related articles - BL Direct - All 2 versions
