- ►nih.gov HJ Tsai, G Sun, DE Weeks, R Kaushal, M … - The American Journal of Human Genetics, 2001 - Elsevier Although genomewide scans have identified several potential chromosomal
susceptibility regions in several human populations, finding a causative gene
for type 2 diabetes has remained elusive. Others have reported a novel ... Cited by 85 - Related articles - BL Direct - All 7 versions
- ►nih.gov Y Song, T Niu, JAE Manson, DJ Kwiatkowski, … - The American Journal of Human Genetics, 2004 - Elsevier The calpain-10 gene (CAPN10) on chromosome 2q37.3 was the first candidate gene
for type 2 diabetes (T2D) identified through a genomewide screen and positional
cloning. One polymorphism (UCSNP-43: G→A) and a specific haplotype ... Cited by 77 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org S Lynn, JC Evans, C White, TM Frayling, AT … - Diabetes, 2002 - Am Diabetes Assoc Variation in the calpain-10 gene (CAPN10) has been shown to be associated with
type 2 diabetes in Mexican-Americans and in at least three Northern European
populations. Studies in nondiabetic Pima Indians showed that one of the ... Cited by 69 - Related articles - BL Direct - All 6 versions
- ►endojournals.org SC Elbein, W Chu, Q Ren, C Hemphill, J … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc The calpain-10 gene (CAPN10) has been implicated in type 2 diabetes (T2DM)
susceptibility by both linkage and association in a Hispanic population from
Starr County Texas. Common intronic variants seem to alter CAPN10 mRNA ... Cited by 68 - Related articles - BL Direct - All 6 versions
- ►endojournals.org A Gonzalez, E Abril, A Roca, MJ Aragon, MJ … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc IN 1935, STEIN AND LEVENTHAL demonstrated that obesity, hirsutism, and
amenorrhea are correlated with polycystic ovaries, identifying a novel syndrome
named Stein-Leventhal or polycystic ovary syndrome (PCOS, MIM 184700). PCOS ... Cited by 66 - Related articles - BL Direct - All 6 versions
- ►eje-online.org [PDF] MT Malecki, DK Moczulski, T Klupa, K Wanic, … - European Journal of Endocrinology, 2002 - EFES Objective: The polymorphisms of two genes have recently been associated with
complex forms of type 2 diabetes mellitus (T2DM): calpain 10 and peroxisome
proliferator-activated receptor-g (PPARg). Cal- pain 10 is a member of a ... Cited by 63 - Related articles - BL Direct - All 9 versions
- ►endojournals.org L Haddad, JC Evans, N Gharani, C Robertson, K … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Variation within the calpain-10 gene (CAPN10) has been proposed to account for
linkage to type 2 diabetes on chromosome 2q in Mexican-Americans, and
associations with diabetes have been reported in several other populations. ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►nih.gov SA Schäfer, O Tschritter, F Machicao, C Thamer … - Diabetologia, 2007 - Springer Page 1. ARTICLE Impaired glucagon-like peptide-1-induced insulin secretion in carriers
of transcription factor 7-like 2 (TCF7L2) gene polymorphisms ... Cited by 54 - Related articles - BL Direct - All 9 versions
- ►endojournals.org C Marshall, GA Hitman, CJ Partridge, A Clark … - Molecular Endocrinology, 2005 - Endocrine Soc Calpain-10 (CAPN10) is the first type 2 diabetes susceptibility gene to be
identified through a genome scan, with polymorphisms being associated with
altered CAPN10 expression. Functional data have been hitherto elusive, but ... Cited by 49 - Related articles - All 5 versions
- ►diabetesjournals.org NJ Cox, MG Hayes, CA Roe, T Tsuchiya, GI … - Diabetes, 2004 - Am Diabetes Assoc The follow-up studies to the original report of association of variation at
calpain 10 (CAPN10) with type 2 diabetes in the Mexican-American population of
Starr County, Texas, encompass a broad range of science. There are ... Cited by 47 - Related articles - BL Direct - All 5 versions
