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Scholar Results 1 - 10 of about 41 citing Mithieux: Intrahepatic mechanisms underlying the effect of metformin in decreasing basal.... (0.09 sec) 

Novel concepts in insulin regulation of hepatic gluconeogenesis

- physiology.org
A Barthel, D Schmoll - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
The regulation of hepatic gluconeogenesis is an important process in the
adjustment of the blood glucose level, and pathological changes in the glucose
production of the liver are a central characteristic in type 2 diabetes. ...
Cited by 123 - Related articles - BL Direct - All 3 versions

Polyunsaturated fatty acyl coenzyme A suppress the glucose-6-phosphatase promoter …

- jbc.org
F Rajas, A Gautier, I Bady, S Montano, G … - Journal of Biological Chemistry, 2002 - ASBMB
Glucose-6-phosphatase confers on gluconeogenic tissues the capacity to release
endogenous glucose in blood. The expression of its gene is modulated by
nutritional mechanisms dependent on dietary fatty acids, with specific ...
Cited by 66 - Related articles - BL Direct - All 8 versions

Liver adenosine monophosphate-activated kinase-{alpha} 2 catalytic subunit is a key target …

- endojournals.org
F Andreelli, M Foretz, C Knauf, PD Cani, C … - Endocrinology, 2006 - Endocrine Soc
The AMP-activated kinase (AMPK) is a serine threonine kinase that functions as a
fuel sensor to regulate energy balance at both cellular and whole-body levels.
Here we studied how hepatic AMPK 2 isoform affects hepatic glucose ...
Cited by 60 - Related articles - All 3 versions

The cellular fate of glucose and its relevance in type 2 diabetes

- endojournals.org
C Bouche, S Serdy, CR Kahn, AB Goldfine - Endocrine reviews, 2004 - Endocrine Soc
Type 2 diabetes is a complex disorder with diminished insulin secretion and
insulin action contributing to the hyperglycemia and wide range of metabolic
defects that underlie the disease. The contribution of glucose metabolic ...
Cited by 51 - Related articles - BL Direct - All 6 versions

Metformin prevents the development of acute lipid-induced insulin resistance in the rat …

- diabetesjournals.org
ME Cleasby, N Dzamko, BD Hegarty, GJ … - Diabetes, 2004 - Am Diabetes Assoc
Metformin reduces the incidence of progression to type 2 diabetes in humans with
obesity or impaired glucose tolerance. We used an animal model to investigate
whether metformin could prevent acute lipid-induced insulin resistance and ...
Cited by 31 - Related articles - BL Direct - All 5 versions

Portal sensing of intestinal gluconeogenesis is a mechanistic link in the diminution of food …

- sbri.fr [PDF] 
G Mithieux, P Misery, C Magnan, B Pillot, A … - Cell Metabolism, 2005 - Elsevier
Protein feeding is known to decrease hunger and subsequent food intake in
animals and humans. It has also been suggested that glucose appearance into
portal vein, as occurring during meal assimilation, may induce comparable ...
Cited by 28 - Related articles - All 12 versions

Metformin delays the manifestation of diabetes and vascular dysfunction in Goto-Kakizaki rats …


P Rösen, NF Wiernsperger, GD Center, G … - Diabetes/Metabolism Reviews - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 26 - Related articles - BL Direct - All 3 versions

The benefits of metformin therapy during continuous subcutaneous insulin infusion treatment …

- Free from Publisher
L Meyer, P Bohme, I Delbachian, P Lehert, N … - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—Treatment with metformin was associated with a reduction in daily
insulin requirements between V0 and V6 of −4.3 ± 9.9 units (−7.8 ± 18%)
compared with an increase with placebo treatment of 1.7 ± 8.3 units (2.8 ...
Cited by 19 - Related articles - BL Direct - All 5 versions

Metformin and its liver targets in the treatment of type 2 diabetes


J Radziuk, CJ Bailey, NF Wiernsperger, JS … - Current Drug Targets-Immune, Endocrine &# 38; …, 2003 - ingentaconnect.com
1 Departments of Medicine and Physiology, Ottawa Hospital and University of
Ottawa, Canada 2 Aston Pharmacy School, Aston University, Birmingham, UK 3 Dept
of Pharmacology, Merck France, Lyon, France 4 Dept of Medicine, University ...
Cited by 18 - Related articles - BL Direct - All 2 versions

Inhibition of phosphoenolpyruvate carboxykinase gene expression by metformin in cultured …


欢迎参加全国医学论文写作研修班 - Chinese medical journal, 2002 - cmj.org
Objective To investigate the effect and mechanism of the antihyperglycemic agent
metformin on the expression of phosphoenolpyruvate carboxykinase (PEPCK) gene in
hepatocytes and to determine whether the effects of metformin in ...
Cited by 15 - Related articles - Cached - BL Direct - All 6 versions


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