- ►fafp.org [PDF] RA DeFronzo - Medical Clinics of North America, 2004 - Elsevier A discussion of the pathogenesis of type 2 diabetes mellitus must start with a
review of mechanisms involved in the maintenance of normal glucose homeostasis
in the basal or postabsorptive state (10–12 h overnight fast) and ... Cited by 692 - Related articles - BL Direct - All 5 versions
G Mingrone, G Rosa, AV Greco, M Manco, N … - Obesity, 2003 - nature.com Results: After BPD, the average weight loss was 38%. Nonprotein RQ was increased
in the postobese subjects (0.73 0.00 vs. 0.83 0.02, p < 0.001). The
intramyocytic triglyceride level dropped (3.66 0.16 to 1.60 0.29 mg/100 mg ... Cited by 244 - Related articles - BL Direct - All 3 versions
- ►endojournals.org H Bays, L Mandarino, RA DeFronzo - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance in liver
and muscle and impaired insulin secretion. Considerable evidence also implicates
deranged adipocyte metabolism and altered fat topography in the ... Cited by 242 - Related articles - All 4 versions
R Weiss, S Dufour, SE Taksali, WV Tamborlane … - The Lancet, 2003 - Elsevier Peripheral glucose disposal was significantly lower in individuals with impaired
than in those with normal glucose tolerance (mean 35·4 [SE 4·0] vs 60·6
[7·2] moles per kg lean body mass per min; p=0·023) owing to a reduction ... Cited by 189 - Related articles - All 6 versions
- ►uni-heidelberg.de [PDF] BH Goodpaster, S Krishnaswami, TB Harris, A … - Archives of internal medicine, 2005 - archinte.highwire.org Methods A cross-sectional study was performed that included a random,
population-based, volunteer sample of Medicare-eligible adults within the
general communities of Pittsburgh, Pa, and Memphis, Tenn. The subjects ... Cited by 156 - Related articles - All 10 versions
- ►fasebj.org RB Ceddia, HA Koistinen, JR Zierath, G … - The FASEB Journal, 2002 - FASEB Obesity is commonly associated with the development of insulin resistance and
diabetes in humans and rodents. Insulin resistance and diabetes are observed in
lipoatrophic individuals or rodent models of lipoatrophy. Here we focus on ... Cited by 138 - Related articles - BL Direct - All 4 versions
- ►angrylapdog.com M Tiikkainen, R Bergholm, S Vehkavaara, A … - Diabetes, 2003 - diabetes.diabetesjournals.org.p.angrylapdog.com Our objective was to determine how 8% weight loss influences subcutaneous,
intra-abdominal, and liver fat (LFAT), as well as features of insulin
resistance, in obese women with high versus low LFAT. A total of 23 women ... Cited by 119 - Related articles - BL Direct - All 7 versions
- ►physiology.org DB Savage, KF Petersen, GI Shulman - Physiological reviews, 2007 - Am Physiological Soc Although abnormal glucose metabolism defines type 2 diabetes mellitus (T2DM) and
accounts for many of its symptoms and complications, efforts to understand the
pathogenesis of T2DM are increasingly focused on disordered lipid ... Cited by 109 - Related articles - BL Direct - All 5 versions
EV Polyzogopoulou, F Kalfarentzos, AG … - Diabetes, 2003 - Am Diabetes Assoc Insulin resistance and loss of glucose-stimulated acute insulin response (AIR)
are the two major and earliest defects in the course of type 2 diabetes. We
investigated whether weight loss after bariatric surgery in patients with ... Cited by 97 - Related articles - BL Direct - All 9 versions
- ►obesityelsalvador.com [PDF] S Moon Han, WW Kim, JH Oh - Obesity surgery, 2005 - Springer Background: In Asia, the type and main cause of obe- sity is different than in
western society.Therefore, the treatment plan should be differentiated, and the
sur- gery for morbid obesity should be carefully chosen. The early results ... Cited by 89 - Related articles - BL Direct - All 6 versions