- ►ahajournals.org J Kim, M Montagnani, KK Koh, MJ Quon - Circulation, 2006 - Am Heart Assoc Endothelial dysfunction contributes to cardiovascular diseases, including
hypertension, atherosclerosis, and coronary artery disease, which are also
characterized by insulin resistance. Insulin resistance is a hallmark of ... Cited by 316 - Related articles - All 9 versions
- ►ahajournals.org S Goetze, A Bungenstock, C Czupalla, F … - Hypertension, 2002 - Am Heart Assoc Migration of endothelial cells (EC) is a key event in angiogenesis that
contributes to neovascularization in diabetic vasculopathy. Leptin induces
angiogenesis and is elevated in obesity and hyperinsulinemia. The ... Cited by 135 - Related articles - BL Direct - All 6 versions
AL Mark, MLG Correia, K Rahmouni, WG … - Journal of hypertension, 2002 - journals.lww.com Leptin, an adipocyte secreted hormone, acts in the hypothalamus to inhibit
appetite and promote thermogenic metabolism, thereby reducing adiposity and body
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- ►endocrinology-journals.org [PDF] J Ren - Journal of Endocrinology, 2004 - Soc Endocrinology The obese gene product, leptin, plays a central role in food intake and energy
metabolism. The physiological roles of leptin in human bodily function have been
broadened over the past decade since leptin was first discovered in 1994. ... Cited by 127 - Related articles - BL Direct - All 10 versions
VA Morrow, F Foufelle, JMC Connell, JR … - Journal of Biological Chemistry, 2003 - ASBMB Recent studies have indicated that endothelial nitric-oxide synthase (eNOS) is
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AMP-activated protein kinase (AMPK) has previously been demonstrated to ... Cited by 122 - Related articles - BL Direct - All 4 versions
P Kougias, H Chai, PH Lin, Q Yao, AB … - Journal of Surgical Research, 2005 - Elsevier Adipose tissue has recently emerged as an active endocrine organ that secretes a
variety of metabolically important substances, collectively called
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- ►ahajournals.org PM Piatti, C Di Mario, LD Monti, G Fragasso, … - Circulation, 2003 - Am Heart Assoc From the Cardiovascular and Metabolic Rehabilitation Unit, Rehabilitation and
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R Komers, S Anderson - American Journal of Physiology- Renal Physiology, 2003 - Am Physiological Soc As an important modulator of renal function and morphology, the nitric oxide
(NO) system has been extensively studied in the diabetic kidney. However, a
number of studies in different experimental and clinical settings have ... Cited by 95 - Related articles - BL Direct - All 4 versions
- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
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J Beltowski - Atherosclerosis, 2006 - Elsevier Leptin, a 167-amino acid peptide hormone produced by white adipose tissue, is
primarily involved in the regulation of food intake and energy expenditure.
Leptin receptors are expressed in many tissues including the cardiovascular ... Cited by 92 - Related articles - All 18 versions