- ►endojournals.org BF Schrijvers, AS De Vriese, A Flyvbjerg - Endocrine reviews, 2004 - Endocrine Soc At present, diabetic kidney disease affects about 15–25% of type 1 and 30–40% of type 2 diabetic
patients. Several decades of extensive research has elucidated various pathways to be implicated in
the development of diabetic kidney ... Cited by 122 - Related articles - All 5 versions
- ►pubget.com [PDF] F Zheng, F Cornacchia, I Schulman, A Banerjee, Q … - Diabetes, 2004 - Am Diabetes Assoc The pathologic hallmarks of diabetic nephropathy are excess mesangial extracellular matrix (ECM) and
mesangial cell proliferation. We previously showed that mesangial cell phenotypic changes play an
important role in the pathogenesis ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►endojournals.org M Karl, M Potier, IH Schulman, A Rivera, H Werner, A … - Endocrinology, 2005 - Endocrine Soc Autocrine activation of the IGF-I system in mesangial cells (MC) promotes glomerular scarring in a
model of type 1 diabetes. Although estrogens protect against progressive nondiabetic
glomerulosclerosis (GS), women with ... Cited by 26 - Related articles - All 6 versions
G Gruden, S Araf, S Zonca, D Burt, S Thomas, L Gnudi … - Kidney international, 2003 - nature.com Both insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) have been
implicated in the pathogenesis of early renal dysfunction in diabetes. We investigated whether IGF-I
affects VEGF gene expression and ... Cited by 20 - Related articles - BL Direct - All 4 versions
R Rabkin, F Schaefer - Growth Hormone & IGF Research, 2004 - Elsevier Both growth hormone (GH) and IGF-1 have major effects on normal kidney growth, structure and
function and participate in the pathogenesis of certain kidney diseases. Furthermore when the
kidneys fail there are profound ... Cited by 19 - Related articles - All 3 versions
TL Vasylyeva, X Chen, RJ Ferry - Growth Hormone & IGF Research, 2005 - Elsevier Quantified by DNA fragmentation ELISA and Annexin V flow cytometry, apoptosis occurred in rat
mesangial cells (RMC) exposed to 2 μg/mL IGFBP-3 for 24 h under high ambient or standard glucose.
Anti-sense IGFBP-3 oligo at 10 ... Cited by 16 - Related articles - All 3 versions
- ►physiology.org [PDF] J Allard, M Buleon, E Cellier, IM Renaud, … - American Journal of …, 2007 - Am Physiological Soc Page 1. 1 ACE inhibitor reduces growth factor receptor expression and signaling but also albuminuria
through B2-kinin glomerular receptor activation in diabetic rats Julien Allard a , Marie Buléon
a , Eric Cellier a , Isabelle Renaud b , Christiane Pecher a , Françoise ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►endojournals.org JR Tejedo, GM Cahuana, R Ramirez, M Esbert, J … - Endocrinology, 2004 - Endocrine Soc Mechanisms involved in the protective action of nitric oxide (NO) in insulin-producing cells are a
matter of debate. We have previously shown that pharmacological inhibition of c-Src cancels the
antiapoptotic action of low and ... Cited by 13 - Related articles - BL Direct - All 8 versions
- ►jbc.org GM Risinger Jr, TS Hunt, DL Updike, EC Bullen, … - Journal of Biological …, 2006 - ASBMB In response to growth factors, vascular smooth muscle cells (VSMCs) undergo a phenotypic modulation
from a contractile, non-proliferative state to an activated, migratory state. This transition is
characterized by changes in their ... Cited by 12 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org SJ Elliot, M Karl, M Berho, X Xia, S Pereria- … - Journal of the American …, 2006 - Am Soc Nephrol Smoking is a known risk factor for the progression of chronic kidney diseases. However, its
independent contribution to the development of ESRD and the underlying molecular mechanism have not
been well elucidated. Although the ... Cited by 9 - Related articles - BL Direct - All 5 versions
