- ►diabetesjournals.org JL Gross, MJ de Azevedo, SP Silveiro, LH … - Diabetes Care, 2005 - Am Diabetes Assoc Diabetic nephropathy is the leading cause of kidney disease in patients starting
renal replacement therapy and affects ∼40% of type 1 and type 2 diabetic
patients. It increases the risk of death, mainly from cardiovascular ... Cited by 214 - Related articles - All 18 versions
ML Caramori, M Mauer - Current opinion in nephrology and hypertension, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic
nephropathy pathology. Clearly, structural changes may be advanced before any
clinical findings are apparent. Not all functional consequences of the ... Cited by 68 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org P Jacobsen, L Tarnow, B Carstensen, P Hovind … - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Originally, we reported patients homozygous for the deletion (D) allele of a
polymorphism in the gene coding for angiotensin-converting enzyme (ACE/ID) to
have an accelerated loss of GFR during 7 yr of ACE inhibition (ACE-I) in 35 ... Cited by 64 - Related articles - BL Direct - All 6 versions
- Free from Publisher S Andersen, L Tarnow, F Cambien, P Rossing, … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—At baseline, GFR, albuminuria, and blood pressure were similar in the
two genotype groups, II versus DD: mean (SD), 86 (22) vs. 88 (24) ml · min –1
· 1.73 m –2 ; median (interquartile range), 1,134 (598–2,023) vs. ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Y Wang, MCY Ng, WY So, PCY Tong, RCW … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS— The frequencies of ACE gene I/D polymorphisms were in Hardy-Weinberg
equilibrium. Patients who developed a renal end point (n = 98) had higher
frequencies of DD genotype (19.4 vs. 10.8%, P = 0.018) and D allele (41.3 ... Cited by 22 - Related articles - All 7 versions
- ►nih.gov P Fioretto, M Mauer - Seminars in nephrology, 2007 - Elsevier The clinical manifestations of diabetic nephropathy, proteinuria, increased
blood pressure, and decreased glomerular filtration rate, are similar in type 1
and type 2 diabetes; however, the renal lesions underlying renal ... Cited by 21 - Related articles - All 9 versions
JN Harvey - Current opinion in nephrology and hypertension, 2003 - journals.lww.com Purpose of review To summarize recent trends in the prevalence of nephropathy
due to diabetes and to assess the causes of these changes. Such analysis may
influence our strategy to reduce the increasing numbers of cases. Recent ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►nih.gov HH Parving, D de Zeeuw, ME Cooper, G … - J Am Soc Nephrol, 2008 - Am Soc Nephrol ABSTRACT Losartan treatment reduced renal outcomes in proteinuric patients with
type 2 diabetes in the Reduction of Endpoints in NIDDM with the Angiotensin II
Antagonist Losartan (RENAAL) study. It is unknown whether an insertion (I)/ ... Cited by 13 - Related articles - All 6 versions
J William, D Hogan, D Batlle - Advances in Chronic Kidney Disease, 2005 - Elsevier Diabetes remains the number one cause of end-stage renal disease worldwide. Only
about one third of diabetic patients develop nephropathy, and the risk appears
to be, in part, genetically determined. In this article, we review clinical ... Cited by 12 - Related articles - All 7 versions
R Castellon, HK Hamdi - Current pharmaceutical design, 2007 - ingentaconnect.com Abstract: The angiotensin converting enzyme (ACE) I/D polymorphism has been one
of the most studied genetic sys- tems. It comprises hundreds of reports and a
myriad of disease associations, including cardiovascular, metabolic, ... Cited by 12 - Related articles - BL Direct - All 3 versions
