- ►nih.gov S Xuan, T Kitamura, J Nakae, K Politi, Y … - Journal of Clinical …, 2002 - Am Soc Clin Investig Defective insulin secretion is a feature of type 2 diabetes that results from inadequate
compensatory increase of β cell mass and impaired glucose-dependent insulin release. β cell
proliferation and secretion are ... Cited by 117 - Related articles - BL Direct - All 11 versions
- ►physiology.org A Nandi, Y Kitamura, CR Kahn, D Accili - Physiological reviews, 2004 - Am Physiological Soc Type 2 diabetes results from a combination of insulin resistance and impaired insulin secretion
(203). The two abnormalities are intertwined, but in most individuals the onset of insulin
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- ►nih.gov N Kubota, Y Terauchi, K Tobe, W Yano, R … - Journal of Clinical …, 2004 - Am Soc Clin Investig 1 Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
2 Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology
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G Bertrand, N Ishiyama, M Nenquin, MA Ravier, JC … - Journal of Biological …, 2002 - ASBMB Glucose increases insulin secretion by raising cytoplasmic Ca 2+ ([Ca 2+ ] i ) in β-cells
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IB Leibiger, B Leibiger, PO Berggren - FEBS letters, 2002 - Elsevier Pancreatic β-cell function is essential for the regulation of glucose homeostasis and its
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- ►nih.gov H Okamoto, D Accili - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Diabetes is associated with defective β cell function and altered β cell mass. The mechanisms
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- ►diabetesjournals.org D Accili - Diabetes, 2004 - Am Diabetes Assoc Type 2 diabetes arises from a combination of impaired insulin action and defective pancreatic
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- ►jbc.org M Nenquin, A Szollosi, L Aguilar-Bryan, J Bryan, JC … - Journal of Biological …, 2004 - ASBMB In normal -cells glucose induces insulin secretion by activating both a triggering pathway (closure
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- ►fasebj.org [PDF] W El-kholy, PE MacDonald, JH Lin, J Wang, J Manning … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-0802fje. Published online February 5, 2003.
The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks Kv currents via a direct mechanism
Wasim El-kholy,* Patrick E. MacDonald,* Jia-Hui Lin,* Jing Wang,* Jocelyn Manning Fox, † ... Cited by 44 - Related articles - BL Direct - All 5 versions
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