EP Haber, HMA Ximenes, J Procopio, CRO … - Journal of cellular physiology, 2003 - interscience.wiley.com Hyperlipidemia is frequently associated with insulin resistance states as found
in type 2 diabetes and obesity. Effects of free fatty acids (FFA) on pancreatic
-cells have long been recognized. Acute exposure of the pancreatic -cell to ... Cited by 75 - Related articles - BL Direct - All 4 versions
- ►stephenminger.com [PDF] HM Milne, CJ Burns, I Kitsou-Mylona, MJ … - Biochemical and Biophysical Research …, 2005 - Elsevier The therapeutic potential of transplantation of insulin-secreting pancreatic
β-cells has stimulated interest in using pluripotent embryonic stem (ES) cells
as a starting material from which to generate insulin secreting cells in ... Cited by 26 - Related articles - All 6 versions
D Muller, GC Huang, S Amiel, PM Jones, SJ … - Diabetes, 2006 - Am Diabetes Assoc Although many studies using rodent islets and insulinoma cell lines have been
performed to determine the role of insulin in the regulation of islet function,
the autocrine effect of insulin on insulin gene expression is still ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►endojournals.org K Song, X Zhang, C Zhao, NT Ang, ZA Ma - Molecular Endocrinology, 2005 - Endocrine Soc Islet Ca 2+ -independent phospholipase A 2 (iPLA 2 ) is postulated to mediate
insulin secretion by releasing arachidonic acid in response to insulin
secretagogues. However, the significance of iPLA 2 signaling in insulin ... Cited by 22 - Related articles - All 4 versions
E Grapengiesser, H Dansk, B Hellman - Biochemical pharmacology, 2004 - Elsevier Pancreatic β-cells respond to glucose stimulation with increase of the
cytoplasmic Ca 2+ concentration ([Ca 2+ ] i ), manifested as membrane-derived
slow oscillations sometimes superimposed with transients of intracellular ... Cited by 14 - Related articles - All 4 versions
- ►diabetesjournals.org SJ Persaud, D Muller, VD Belin, I Kitsou- … - Diabetes, 2007 - Am Diabetes Assoc The roles played by arachidonic acid and its cyclooxygenase (COX)-generated and
lipoxygenase (LOX)-generated metabolites have been studied using rodent islets
and insulin-secreting cell lines, but very little is known about COX and ... Cited by 12 - Related articles - BL Direct - All 5 versions
J Cantley, AI Choudhury, H Asare-Anane, C … - Diabetologia, 2007 - Springer Page 1. ARTICLE Pancreatic deletion of insulin receptor substrate 2 reduces beta
and alpha cell mass and impairs glucose homeostasis in mice ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►physiology.org MJ Luther, E Davies, D Muller, M Harrison, … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Cell-to-cell interactions play an important role in the development and
maintenance of the -cell phenotype. Here, we have investigated whether
E-cadherin plays a role in regulating the growth of insulin-secreting MIN6 ... Cited by 12 - Related articles - All 5 versions
- ►physiology.org K Juhl, M Høy, HL Olsen, K Bokvist, AM … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Using capacitance measurements, we investigated the effects of intracellularly
applied recombinant human cytosolic phospholipase A 2 (cPLA 2 ) and its
lipolytic products arachidonic acid and lysophosphatidylcholine on Ca 2 + - ... Cited by 11 - Related articles - BL Direct - All 3 versions
