- ►cell.com KA Moynihan, AA Grimm, MM Plueger, E Bernal … - Cell Metabolism, 2005 - Elsevier Sir2 NAD-dependent deacetylases connect transcription, metabolism, and aging.
Increasing the dosage or activity of Sir2 extends life span in yeast, worms, and
flies and promotes fat mobilization and glucose production in mammalian ... Cited by 136 - Related articles - All 18 versions
NE Zachara, GW Hart - BBA-General Subjects, 2004 - Elsevier Myriad nuclear and cytoplasmic proteins in metazoans are modified on Ser and Thr
residues by the monosaccharide O-linked β-N-acetylglucosamine (O-GlcNAc). The
rapid and dynamic change in O-GlcNAc levels in response to extracellular ... Cited by 107 - Related articles - All 5 versions
G Xu, W Zhang, P Bertram, XF Zheng, H … - International journal of oncology, 2004 - umdnj.edu Abstract. The protein synthetic machinery is activated by a variety of genetic
alterations during tumor progression and represents an attractive target for
cancer therapy. The mammalian target of rapamycin (mTOR) plays an important ... Cited by 81 - Related articles - View as HTML - BL Direct - All 4 versions
R Hyde, PM Taylor, HS Hundal - Biochemical Journal, 2003 - pubmedcentral.nih.gov Amino acid availability regulates cellular physiology by modu- lating gene
expression and signal transduction pathways. How- ever, although the signalling
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AJ Meijer, PF Dubbelhuis - Biochemical and Biophysical Research …, 2004 - Elsevier It has become clear in recent years that amino acids are not only important as
substrates for various metabolic pathways but that they can also activate a
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B Wicksteed, C Alarcon, I Briaud, MK Lingohr … - Journal of Biological Chemistry, 2003 - ASBMB Proinsulin biosynthesis is regulated in response to nutrients, most notably
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CK Tsang, H Qi, LF Liu, XFS Zheng - Drug discovery today, 2007 - Elsevier The macrolide rapamycin is used clinically to treat graft rejection and
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- ►physiology.org LM Dickson, CJ Rhodes - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc The control of pancreatic -cell growth and survival in the adult plays a pivotal
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