- ►physiology.org JF Oram, JW Heinecke - Physiological reviews, 2005 - Am Physiological Soc Blood high-density lipoprotein (HDL) levels are inversely related to risk for cardiovascular
disease, implying that factors associated with HDL metabolism are atheroprotective. One of these
factors is ATP-binding cassette transporter A1 (ABCA1), a cell membrane protein that ... Cited by 156 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org JF Oram - Arteriosclerosis, Thrombosis, and Vascular Biology, 2003 - Am Heart Assoc It is widely believed that HDL protects against atherosclerosis by removing excess cholesterol
from arterial cells. Lipid-poor HDL apolipoproteins promote efflux of cholesterol,
phospholipids, and other lipophilic molecules from cells by an active process mediated by ... Cited by 144 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org N Wang, AR Tall - Arteriosclerosis, thrombosis, and vascular biology, 2003 - Am Heart Assoc •Yancy PG, Bortnick AE, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Rothblat GH. Importance
of different pathways of cellular cholesterol efflux. 2003;23:712–719. •Oram JF. HDL Apolipoproteins
and ABCA1: partner in the removal of excess cellular cholesterol. 2003;23:720–727. ... Cited by 145 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org JF Oram, AM Vaughan - Circulation research, 2006 - Am Heart Assoc A hallmark of atherosclerotic cardiovascular disease (CVD) is the accumulation of cholesterol
in arterial macrophages. Factors that modulate circulating and tissue cholesterol levels have
major impacts on initiation, progression, and regression of CVD. Four members of the ... Cited by 105 - Related articles - All 8 versions
JY Lee, JS Parks - Current opinion in lipidology, 2005 - pdfs.journals.lww.com Purpose of review ATP-binding cassette transporter AI (ABCA1)-mediated assembly of phospholipid
and free cholesterol with apoA-I plays an important role in HDL biogenesis. This review focuses
on recent progress in ABCA1-mediated HDL formation and regulation of ABCA1 ... Cited by 87 - Related articles - All 6 versions
- ►pasteur.ac.ir [PDF] G Schmitz, T Langmann - BBA-Molecular and Cell Biology of Lipids, 2005 - Elsevier The ATP-binding cassette transporters, ABCA1 and ABCG1, are major players in mediating cellular
efflux of phospholipids and cholesterol to apoA-I containing lipoproteins including preβ-HDL
and αHDL and thereby exert important antiatherogenic properties. Although the exact ... Cited by 86 - Related articles - All 4 versions
L Rohrer, M Hersberger, A von … - Current opinion in …, 2004 - journals.lww.com Recent findings: Elevated levels of non-esterified fatty acids and disturbed insulin action contribute
to low HDL-cholesterol in diabetes mellitus by modifying lipolysis, apolipoprotein AI
production, as well as the activities of adenosine triphosphate-binding cassette ... Cited by 84 - Related articles - BL Direct - All 5 versions
- ►jlr.org Y Wang, B Kurdi-Haidar, JF Oram - The Journal of Lipid Research, 2004 - ASBMB Abnormal HDL metabolism among patients with diabetes and insulin resistance may contribute
to their increased risk of atherosclerosis. ATP binding cassette transporter A1 (ABCA1) mediates
the transport of cholesterol and phospholipids from cells to HDL apolipoproteins and thus ... Cited by 54 - Related articles - BL Direct - All 5 versions