- ►ahajournals.org AH Berg, PE Scherer - Circulation Research, 2005 - Am Heart Assoc Mounting evidence highlights the role of adipose tissue in the development of a
systemic inflammatory state that contributes to obesity-associated vasculopathy
and cardiovascular risk. Circulating mediators of inflammation participate ... Cited by 428 - Related articles - All 10 versions
DB Carr, KM Utzschneider, RL Hull, K Kodama … - Diabetes, 2004 - Am Diabetes Assoc The underlying pathophysiology of the metabolic syndrome is the subject of
debate, with both insulin resistance and obesity considered as important
factors. We evaluated the differential effects of insulin resistance and ... Cited by 346 - Related articles - BL Direct - All 5 versions
- ►endojournals.org JH Lee, JL Chan, N Yiannakouris, M … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Resistin is a novel adipocyte-secreted hormone proposed to link obesity with
diabetes. Studies in mice have revealed conflicting data however, and the
physiological role of circulating resistin in humans remains unknown. We ... Cited by 263 - Related articles - BL Direct - All 6 versions
CM Steppan, MA Lazar - Journal of Internal Medicine, 2004 - interscience.wiley.com Obesity and noninsulin-dependent diabetes mellitus are globally epidemic.
Insulin resistance is a major contributor to the pathogenesis of type II
diabetes and plays a role in numerous other metabolic disorders including ... Cited by 208 - Related articles - BL Direct - All 4 versions
LK Heilbronn, E Ravussin - American Journal of Clinical Nutrition, 2003 - Am Soc Nutrition Calorie restriction (CR) extends life span and retards age-related chronic
diseases in a variety of species, including rats, mice, fish, flies, worms, and
yeast. The mechanism or mechanisms through which this occurs are unclear. ... Cited by 188 - Related articles - BL Direct - All 9 versions
- ►uni-heidelberg.de [PDF] BH Goodpaster, S Krishnaswami, TB Harris, A … - Archives of internal medicine, 2005 - archinte.highwire.org Methods A cross-sectional study was performed that included a random,
population-based, volunteer sample of Medicare-eligible adults within the
general communities of Pittsburgh, Pa, and Memphis, Tenn. The subjects ... Cited by 157 - Related articles - All 10 versions
D Festi, A Colecchia, T Sacco, M Bondi, E … - Obesity reviews, 2004 - pt.wkhealth.com Non-alcoholic fatty liver disease is a new clinicopathological condition of
emerging importance, now recognized as the most common cause of abnormal liver
tests. It is characterized by a wide spectrum of liver damage: simple ... Cited by 114 - Related articles - BL Direct - All 6 versions
- ►cell.com M Lafontan, M Berlan - Trends in pharmacological sciences, 2003 - Elsevier Obesity is an increasing health problem in many countries. Striking differences
exist in the magnitude of the impact of different obesities on comorbidities.
Individuals with peripheral obesity ('pears') possess fat distributed ... Cited by 109 - Related articles - All 7 versions
- ►upenn.edu [PDF] RR Banerjee, MA Lazar - Journal of Molecular Medicine, 2003 - Springer Insulin resistance, the inability of target tissues to re- spond normally to
insulin, is central to the pathophysiol- ogy of type 2 diabetes [1], but its
molecular basis re- mains poorly understood. Classically, the explanation ... Cited by 93 - Related articles - BL Direct - All 4 versions
MB Snijder, RM Van Dam, M Visser, JC … - International journal of epidemiology, 2006 - IEA Since the 1950s it has been recognized that apart from overall obesity the
distribution of body fat can influence disease risk. 5 In particular an
abdominal fat distribution is associated with metabolic disturbances and ... Cited by 89 - Related articles - BL Direct - All 8 versions
